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Cleveland Browns at Pittsburgh Steelers: Predictions, picks and odds for NFL Week 2 game

The Cleveland Browns (1-0) are in for another AFC North matchup after a statement win in Week 1.

Deshaun Watson and Co. take on the Pittsburgh Steelers (0-1) in the final game of Week 2 on Monday night. They won the Battle of Ohio for their second straight season opener victory by dismantling the Cincinnati Bengals just days after Joe Burrow became the highest-paid player in the NFL.

The Steelers will seek redemption at Acrisure Stadium after dropping their home opener with a lowly performance against the San Francisco 49ers. There was one bright spot when TJ Watt tied the franchise record for career sacks with three takedowns of Brock Purdy.

The Browns and Steelers split the series last year as both missed the playoffs.

Will Pittsburgh be able to brush off its wounds or will the Dawg Pound give them another licking?

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Steelers vs. Browns odds, moneyline, over/under

The Cleveland Browns are favorites to defeat the Pittsburgh Steelers, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

  • Spread: Browns (-2.5)

  • Moneyline: Browns (-140); Steelers (+115)

  • Over/under: 38.5

Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

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Pittsburgh Steelers wide receiver George Pickens catches a pass for a two point conversion as Cleveland Browns cornerback Greg Newsome II applies coverage during the team's January 2023 matchup.
Pittsburgh Steelers wide receiver George Pickens catches a pass for a two point conversion as Cleveland Browns cornerback Greg Newsome II applies coverage during the team's January 2023 matchup.

NFL Week 2 odds, predictions and picks

Vikings vs. Eagles | Packers vs. Falcons | Raiders vs. Bills | Ravens vs. Bengals | Seahawks vs. Lions | Colts vs. Texans | Chiefs vs. Jaguars | Bears vs. Buccaneers | Chargers vs. Titans | Giants vs. Cardinals | 49ers vs. Rams | Jets vs. Cowboys | Commanders vs. Broncos | Dolphins vs. Patriots | Saints vs. Panthers | Browns vs. Steelers

Lorenzo Reyes: Steelers 21, Browns 20

Pittsburgh was arguably the worst letdown of Week 1 after a positive offseason. I think the Steelers will be much better and will bounce back. Cleveland was impressive in its opener against the Bengals, but I still think the Browns are vulnerable on offense. Look for Kenny Pickett to get George Pickens involved much earlier.

Tyler Dragon: Browns 21, Steelers 20

The Browns are trying to prove that they are a legitimate contender in the AFC North. They made a statement beating down the division rival Bengals. The Browns will send an even bigger message if they begin the season 2-0 in the AFC North.

Victoria Hernandez: Browns 21, Steelers 17

Both teams surprised in Week 1, for quite opposite reasons. I expect the Steelers to show a little more life than their embarrassing season opener, but Cleveland's confidence will lead them to win on the road.

Jordan Mendoza: Browns 20, Steelers 16

The Browns defense didn’t let the Bengals breathe in a dominant win, while Pittsburgh was overpowered by San Francisco. Riding the momentum, Cleveland gets another divisional win thanks to its defense wrecking havoc.

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This article originally appeared on USA TODAY: Cleveland Browns at Pittsburgh Steelers: Game predictions, picks, odds