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Kansas City Chiefs at Los Angeles Chargers picks, predictions: Who wins NFL Week 18 game?

The Kansas City Chiefs and Los Angeles Chargers play on Sunday, Jan. 7 at SoFi Stadium in a game on the NFL Week 18 schedule.

Which team will win the Week 18 NFL game?

Check out these NFL Week 18 picks and NFL Week 18 predictions for the game, which can be seen at 2:25 p.m. MST on CBS (stream with free trial from FUBO).

The Chargers are a 3.5-point favorite over the Chiefs in NFL Week 18 odds for the game, courtesy of BetMGM Sportsbook.

Los Angeles is -190 on the moneyline, while Kansas City is +155.

The over/under (point total) is set at 35 points.

The Chiefs are coming off a 25-17 win against the Cincinnati Bengals in their NFL Week 17 game.

The Chargers are coming off a 16-9 loss against the Denver Broncos.

NFL Week 18 picks: Steelers at Ravens | Texans at Colts | Falcons at Saints | Browns at Bengals | Jaguars at Titans | Vikings at Lions | Jets at Patriots | Buccaneers at Panthers | Bears at Packers | Chiefs at Chargers | Eagles at Giants | Cowboys at Commanders | Broncos at Raiders | Rams at 49ers | Seahawks at Cardinals | Bills at Dolphins | Power rankings | Playoffs: AFC | NFC | Odds | TV

The Arizona Republic: Chargers 21, Chiefs 14

Jeremy Cluff writes: "The Chiefs are locked into their playoff spot and will likely rest key players, giving the Chargers the opportunity to end a disappointing season with a win."

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Bookies.com: Bet the under on Chargers vs. Chiefs NFL Week 18 game

Bill Speros writes: "Taylor Swift and Travis Kelce may opt to spend the weekend on Catalina Island. The AFC West champion Chiefs (What Else Is New?) are locked into the No. 3 spot in the AFC. The August AFC West Champion Chargers are on to 2024 - and maybe Bill Belichick as their new head coach. No doubt Patrick Mahomes and Andy Reid want to get some more work in on offense, but expect to see more scrubs in the second here than you would at Cedars-Sinai Medical Center. The Chiefs' under-appreciated defense may pitch a shutout here. It's the only reason why KC is the postseason this season."

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Sports Betting Dime: Chiefs 28.4, Chargers 13.4

The site's formula predicts that the Chiefs will win the NFL Week 18 game against the Chargers.

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Will the Los Angeles Chargers beat the Kansas City Chiefs on Sunday? NFL Week 18 picks, predictions and odds weigh in on the game.
Will the Los Angeles Chargers beat the Kansas City Chiefs on Sunday? NFL Week 18 picks, predictions and odds weigh in on the game.

ESPN: Chiefs have a 76.6% chance to beat Chargers on Sunday

The site gives the Chargers a 23.2% shot at winning the Week 18 NFL game.

NFL Week 18 odds: Point spreads, moneylines, over/unders for betting on games

NFL Week 18 schedule: Television channels, how to watch, stream games

Pro Football Network: Odds favor Chargers in NFL Week 18 vs. Chiefs

Kyle Soppe writes: "At least one team has scored 27+ points in six straight games in this series with the road team winning four of those contests. Unders are 11-6 since the start of 2021 when the Chargers play a divisional opponent (fifth-highest hit rate)."

STREAM THE GAME: Watch Chiefs at Chargers live with FUBO (free trial)

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Kansas City Chiefs at Los Angeles Chargers picks, odds for NFL Week 18