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NFL Week 4 odds: Point spreads, moneylines, over/unders for betting on games

Jeremy Cluff, Arizona Republic
·3 min read
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The NFL Week 4 schedule has some very interesting games, and some very interesting betting lines.

Who is the favorite in each game?

What do the betting odds say about each game?

The biggest point spreads of the week are the San Francisco 49ers as a 14-point favorite against the Arizona Cardinals and the Kansas City Chiefs as a 9-point favorite against the New York Jets.

The smallest lines include the Indianapolis Colts (-1) over the Los Angeles Rams, the Detroit Lions (-1.5) over the Green Bay Packers and the Seattle Seahawks (-1.5) over the New York Giants.

Some games are expected to have high point totals, with the over/under in the Miami Dolphins vs. Buffalo Bills game set at 53.5 points and the over/under in the Las Vegas Raiders vs. Los Angeles Chargers game set at 50.5 points.

Other games could be very low scoring, with the point total set at 40.5 in the Pittsburgh Steelers vs. Houston Texans game and at 40.5 in the Tampa Bay Buccaneers vs. New Orleans Saints game.

Take a look at the point spread, moneyline and over/under for every game on the NFL Week 4 schedule, courtesy of BetMGM Sportsbook. Click on each game for NFL Week 4 picks and predictions for that game.

NFL Week 4 picks: Lions at Packers | Falcons at Jaguars | Dolphins at Bills | Vikings at Panthers | Broncos at Bears | Ravens at Browns | Steelers at Texans | Rams at Colts | Buccaneers at Saints | Commanders at Eagles | Bengals at Titans | Raiders at Chargers | Patriots at Cowboys | Cardinals at 49ers | Chiefs at Jets | Seahawks at Giants

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NFL Week 4 point spreads:

NFL Week 4 schedule: Television channels, how to watch, stream games

NFL Week 4 picks, predictions: Lions at Packers, Dolphins at Bills among must-see games

Travis Kelce and the Kansas City Chiefs are favored over the New York Jets in NFL Week 4 odds.
Travis Kelce and the Kansas City Chiefs are favored over the New York Jets in NFL Week 4 odds.

NFL Week 4 moneylines:

NFL power rankings Week 4: Raising Arizona, dropping Dallas after Cardinals' shocking win

NFL Week 4 over/unders (point totals):

  • Detroit Lions at Green Bay Packers: 44.5

  • Atlanta Falcons at Jacksonville Jaguars: 43.5

  • Miami Dolphins at Buffalo Bills: 53.5

  • Minnesota Vikings at Carolina Panthers: 44.5

  • Denver Broncos at Chicago Bears: 45.5

  • Baltimore Ravens at Cleveland Browns: 42.5

  • Pittsburgh Steelers at Houston Texans: 40.5

  • Los Angeles Rams at Indianapolis Colts: 45

  • Tampa Bay Buccaneers at New Orleans Saints: 40.5

  • Washington Commanders at Philadelphia Eagles: 44.5

  • Cincinnati Bengals at Tennessee Titans: 42.5

  • Las Vegas Raiders at Los Angeles Chargers: 50.5

  • New England Patriots at Dallas Cowboys: 41.5

  • Arizona Cardinals at San Francisco 49ers: 42

  • Kansas City Chiefs at New York Jets: 42.5

  • Seattle Seahawks at New York Giants: 45

NOTE: Every Sunday and Monday NFL game can be streamed locally on FUBO, click here for a free trial

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: NFL Week 4 odds: Point spreads, moneylines, over/unders for betting