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Indianapolis Colts at New England Patriots predictions, odds: Who wins NFL Week 10 game?

The Indianapolis Colts and New England Patriots play on Sunday, Nov. 12 at Deutsche Bank Park in Frankfurt, Germany in the first game on the Sunday NFL Week 10 schedule.

Which team will win the Week 10 NFL game?

Check out these NFL Week 10 picks and NFL Week 10 predictions for the game, which can be seen at 7:30 a.m. MST on NFL Network (stream with free trial from FUBO).

The Colts are a 2-point favorite over the Patriots in NFL Week 10 odds for the game, courtesy of BetMGM Sportsbook.

Indianapolis is -130 on the moneyline, while New England is +110.

The over/under (point total) is set at 43.5 points.

The Colts are coming off a 27-13 win against the Carolina Panthers in their NFL Week 9 game.

The Patriots are coming off a 20-17 loss against the Washington Commanders.

NFL Week 10 picks: Panthers at Bears | Colts at Patriots | Browns at Ravens | Texans at Bengals | 49ers at Jaguars | Saints at Vikings | Packers at Steelers | Titans at Buccaneers | Falcons at Cardinals | Lions at Chargers | Giants at Cowboys | Commanders at Seahawks | Jets at Raiders | Broncos at Bills | Betting lines | How to watch on TV | NFL power rankings | Win probabilities | Playoff picture

NFL Week 10 picks: Who wins Browns-Ravens, Texans-Bengals, 49ers-Jaguars, Saints-Vikings?

The Arizona Republic: Colts 27, Patriots 17

Jeremy Cluff writes: "The Patriots have only scored 135 points this season. That's not good. The Colts have at least shown an ability to put points on the scoreboard. That's good enough for us to go with Indianapolis."

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Bookies.com: Take the Colts to cover vs. Patriots

Bill Speros writes: "The Patriots may want to stay overseas with a loss here. The Colts will try to win overseas with Gardner Minshew at QB. Bill Belichick appears to have lost his old magic. His vaunted defense got torn up by Sam Howell and the Commanders Sunday. New England is scoring just 14.8 PPG (31st), while its famed defense is allowing 26.0 PPG (26th). The Patriots are an AFC-worst 2-7 outright and ATS and are dead last in the playoff hunt. They opened as 5-point favorites. The Colts are now -2. Geht Colts!"

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Sports Betting Dime: Colts 27.7, Patriots 19.4

The site's formula predicts that the Colts will win the NFL Week 10 game against the Patriots.

NFL Week 10 predictions: ESPN matchup predictor's picks, win probabilities for this week

NFL Week 10 picks, predictions and odds weigh in on Sunday's game in Germany between the New England Patriots and Indianapolis Colts.
NFL Week 10 picks, predictions and odds weigh in on Sunday's game in Germany between the New England Patriots and Indianapolis Colts.

ESPN: Colts have a 52% chance to beat Patriots on Sunday

The site gives the Patriots a 47.6% shot at winning the Week 10 NFL game.

NFL Week 10 odds: Point spreads, moneylines, over/unders for betting on games

CBS Sports: Odds favor Colts in NFL Week 10 vs. Patriots

Tyler Sullivan writes: "This game will be held in Frankfurt for the second and final Germany game of the 2023 season. While New England is technically the home team, this is a neutral site that has the Colts favored by 1.5 points. Indy has been a far more competitive team in 2023 compared to the Patriots, owning a 4-5 record that includes a Week 9 road win over the Panthers. As for New England, it fell at home to the Commanders. With a 2-7 ATS record, the Patriots are tied for the second-worst ATS mark in the league. The Colts, on the other hand, are 5-4 ATS and the Over is tied for a league-best 6-3."

NFL Week 10 schedule: Television channels, how to watch, stream games

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STREAM THE GAME: Watch Colts at Patriots live with FUBO (free trial)

WANNA BET? How to bet on NFL games in 2023

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Indianapolis Colts at New England Patriots picks, odds for NFL Week 10