Tampa Bay Buccaneers at New England Patriots odds, picks and prediction

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The Tampa Bay Buccaneers (2-1) and New England Patriots (1-2) meet on Sunday Night Football at Gillette Stadium in Week 4. Kickoff is scheduled for 8:20 p.m. ET. Below, we look at the Buccaneers vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Buccaneers are looking to bounce back after suffering their first loss of the season on the road against the Los Angeles Rams. The Over connected in each of the three outings for Tampa Bay to date.

The Patriots will get a chance to face QB Tom Brady on their home field. You might have heard he used to play in New England. The new signal-caller, QB Mac Jones, has been a bit uneven so far, and the Patriots are 0-2 straight up and against the spread through two home games. The Under is 3-0 in three outings for New England.

Odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 9:40 a.m. ET.

Money line: Buccaneers -300 (bet $300 to win $100) | Patriots +230 (bet $100 to win $230)

Against the spread (ATS): Buccaneers -6.5 (-120) | Patriots +6.5 (-105)

Over/Under (O/U): 49.5 (O: -110 | U: -110)

Key injuries

Buccaneers

  • RB Giovani Bernard (knee) out

  • TE Rob Gronkowski (ribs) doubtful

  • LB Jason Pierre-Paul (shoulder) questionable

  • CB Jamel Dean (knee) out

Patriots

  • LB Kyle Van Noy (groin) questionable

  • RB James White (hip) out

  • LB Ja’Whaun Bentley (shoulder) questionable

  • OL Trent Brown (calf) questionable

  • PK Nick Folk (knee) questionable

  • OL Isaiah Wynn (knee) questionable

  • DB Kyle Dugger (hamstring) questionable

  • LB Josh Uche (back) questionable

  • DB J.C. Jackson (knee) questionable

Odds, lines, predictions and picks

Prediction

Buccaneers 34, Patriots 17

Money line

The homecoming for Brady is going to be a successful one, as the Buccaneers (-320) bounce back from a defeat in a marquee game last weekend in Los Angeles.

However, you can’t risk more than three times your potential return on a road team, even with a legend like Brady under center in his old stomping grounds with a chip on his shoulder. There is just no value here.

AVOID, and look to the spread.

Against the spread

The BUCCANEERS -7.5 (-102) are an amazing value. The Patriots defense has been stout, but the offense is just too error-prone, and that’s not going to cut the mustard against Brady. He’ll make Jones and the Patriots pay while magnifying every error.

The Bucs were 4-1 SU/5-0 ATS after a straight-up loss last season, so don’t expect a losing skid. Brady just doesn’t allow that to happen.

Over/Under

The OVER 49.5 (-108) is the lean but go lightly. The New England defense has been stout, but it has been all Over all the time in prime-time games so far this NFL season.

The Over is 8-2 in games under the lights following Week 4’s Thursday Night Football matchup. Expect another shootout with Brady and the defending champs showing out.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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This article originally appeared on USA TODAY: Buccaneers at Patriots odds, picks and prediction