Green Bay Packers at Detroit Lions picks, predictions, odds: Who wins NFL Week 12 game?

The Green Bay Packers and Detroit Lions play on Thursday, Nov. 23 at Ford Field in the first game on the NFL Week 12 schedule.

Which team will win the Thanksgiving Day game?

Check out these NFL Week 12 picks and NFL Week 12 predictions for the game, which can be seen at 10:30 a.m. MST on FOX (stream with free trial from FUBO).

The Lions are a 7.5-point favorite over the Packers in NFL Week 12 odds for the game, courtesy of BetMGM Sportsbook.

Detroit is -375 on the moneyline, while Green Bay is +300.

The over/under (point total) is set at 46 points.

The Packers are coming off a 23-20 win against the Los Angeles Chargers in their NFL Week 11 game.

The Lions are coming off a 31-26 win against the Chicago Bears.

NFL Week 12 picks: Packers at Lions | Commanders at Cowboys | 49ers at Seahawks | Dolphins at Jets | Saints at Falcons | Steelers at Bengals | Jaguars at Texans | Buccaneers at Colts | Patriots at Giants | Panthers at Titans | Rams at Cardinals | Browns at Broncos | Chiefs at Raiders | Bills at Eagles | Ravens at Chargers | Bears at Vikings | NFL power rankings | NFL odds | NFL schedule

The Arizona Republic: Lions 24, Packers 21

Jeremy Cluff writes: "We still don't know how the Lions rallied to beat the Bears. This is lining up to be a very special season in Detroit and it will continue against the Packers."

NFL Week 12 picks, predictions: Lions, Cowboys, 49ers among winners of this week's games?

Bookies.com: Take the Lions to cover against Packers

Bill Speros writes: "This game is a terrific opportunity to grab a win and then enjoy an extended break. Jordan Love can throw the ball deep, but he may not have enough time to do much of anything. Nor can he keep up with the Lions offensive circus. This is a steep line, and an early game on a short week, but the Lions are hungry for a big win on national TV. The Lions have covered in 6 straight at home vs. the Packers."

NFL power rankings Week 12: Broncos, Lions, Texans, Browns keep winning streaks alive

Sports Betting Dime: Lions 20.9, Packers 14.5

The site's formula predicts that the Lions will win the NFL Week 12 game against the Packers.

NFL Week 12 odds: Point spreads, moneylines, over/unders for betting on games

ESPN: Lions have a 64% chance to beat Packers on Thanksgiving Day

The site gives the Packers a 35.7% shot at winning the Week 12 NFL game.

NFL Week 12 schedule: Television channels, how to watch, how to stream games this week

CBS Sports: odds favor Lions in NFL Week 12 vs. Packers

Tyler Sullivan writes: "The Lions have won four straight against the Packers and folks do seem to be backing Detroit in this Thanksgiving matchup. After opening at Lions -7, the line has crossed a key threshold and now sits at Lions -7.5. Dan Campbell's team is 3-2 ATS at home and hosts a Packers team that is 2-3 ATS on the road. Meanwhile, the total has held at 45.5 coming out of Sunday. As the home team, the Over is 3-2 for the Lions this season and is 3-2 for the Packers outside of Lambeau Field. When these teams met back in Week 4, the Lions edged out Green Bay, 34-20."

STREAM THE GAME: Watch Packers at Lions live with FUBO (free trial)

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Green Bay Packers at Detroit Lions picks, predictions for NFL Week 12