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Dallas Cowboys at Philadelphia Eagles: Predictions, picks and odds for NFL Week 6 matchup

Cooper Rush and the Dallas Cowboys (4-1) hit the road and travel to Philadelphia to take on Jalen Hurts' Eagles (5-0) in a highly-anticipated game with massive NFC East ramifications.

Can Rush, who is 5-0 in his career as an NFL starter, keep the magic going against the league's lone undefeated team? Hurts, A.J. Brown and the Eagles will look to keep Philadelphia's momentum going in a pivotal intradivisional contest. The game is scheduled to kick off Sunday at 8:25 p.m. ET from Lincoln Financial Field.

Here's a look at the betting details and USA TODAY's NFL staff picks for the Cowboys vs. Eagles Week 6 game:

Cowboys at Eagles odds, moneyline and over/under

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Commanders vs. BearsPatriots vs. BrownsBuccaneers vs. Steelers Ravens vs. Giants | Vikings vs. DolphinsJets vs. Packers49ers vs. Falcons | Bengals vs. Saints | Jaguars vs. ColtsCardinals vs. SeahawksPanthers vs. RamsBills vs. Chiefs | Cowboys vs. EaglesBroncos vs. Chargers

Lorenzo Reyes: Eagles 22, Cowboys 20

Another excellent matchup, the Cowboy defense is the real wild card here. They can generate pressure on anyone and Philadelphia’s offensive line is a little banged up. But even if Dak Prescott makes his return, I like Philadelphia’s weapons on offense a little more. Jalen Hurts’ versatility presents problems. This one, however, should be pretty close.

Quarterback Jalen Hurts has the Eagles off to a 3-0 start.
Quarterback Jalen Hurts has the Eagles off to a 3-0 start.

Safid Deen: Eagles 28, Cowboys 24

The Cowboys’ luck has to run out at some point, right? I thought it would’ve happened weeks ago, but Dallas is 4-1. Their defense is going to play Philly tough. But Jalen Hurts and the Eagles are in for a special season.

Lance Pugmire: Eagles 24, Cowboys 20

Jalen Hurts has his squad atop NFL power rankings, and now he confronts a streaking divisional foe hell bent to win with defensive bullying. Winning here at home affirms Philadelphia is the NFC team to beat.

Jarrett Bell: Cowboys 20, Eagles 17

Nate Davis: Eagles 23, Cowboys 17

Tyler Dragon: Eagles 24, Cowboys 20

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This article originally appeared on USA TODAY: Dallas Cowboys at Philadelphia Eagles: Game predictions, picks, odds