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College Wire regional editor Patrick Conn makes his Week 1 predictions

While some teams kicked off the season in week 0, week 1 is the official starting point for the rest of the college football landscape. There are some key matchups this week that will set the tone for the 2022 campaign.

The trio of big matchups will begin on Saturday when the Oregon Ducks and Georgia Bulldogs meet in Atlanta at 3:30 p.m. ET. The next features the Utah Utes heading into the Swamp to meet the Florida Gators at 7:00 p.m. ET. The final matchup features two top-five ranked teams.

The Notre Dame Fighting Irish head into Columbus to take on the Ohio State Buckeyes. Former Buckeyes linebacker Marcus Freeman will lead the Irish into this showdown in hostile territory.

Regional editor Patrick Conn breaks down 22 games that feature teams covered on the College Wire network. Who has the upper hand this weekend?

*Editor’s Note: Games are listed in order of kickoff time*

Ball State at Tennessee

Calvin Mattheis/News Sentinel / USA TODAY NETWORK

Game Time: 7:00 p.m. ET (Thursday)

Prediction: Tennessee

X-Factor: Hendon Hooker

For more on Tennessee check out Vols Wire

Penn State at Purdue

Matthew OHaren-USA TODAY Sports

Game Time: 8:00 p.m. ET (Thursday)

Prediction: Purdue

X-Factor: Aidan O’Connell

For more on Penn State check out Nittany Lions Wire

Western Michigan at No. 14 Michigan State

Junfu Han / USA TODAY NETWORK

Game Time: 7:00 p.m. ET (Friday)

Prediction: Michigan State

X-Factor: Jayden Reed

For more on Michigan State check out Spartans Wire

TCU at Colorado

Ron Chenoy-USA TODAY Sports

Game Time: 10:00 p.m. ET

Prediction: TCU

X-Factor: Quentin Johnston

For more on the Buffs check out Colorado Buffaloes Wire

South Dakota State at Iowa

Hawk Central-USA TODAY Network

Game Time: 12:00 p.m. ET

Prediction: Iowa

X-Factor: Sam LaPorta

For more on Iowa check out Hawkeyes Wire

North Carolina at Appalachian State

Rob Kinnan-USA TODAY Sports

Game Time: 12:00 p.m. ET

Prediction: North Carolina

X-Factor: Drake Maye

For more on North Carolina check out Tar Heels Wire

Rutgers at Boston College

Nathan Ray Seebeck-USA TODAY Sports

Game Time: 12:00 p.m. ET

Prediction: Boston College

X-Factor: Phil Jurkovec

For more on the Scarlet Knights check out Rutgers Wire

Sam Houston at No. 7 Texas A&M

Maria Lysaker-USA TODAY Sports

Game Time: 12:00 p.m. CT

Prediction: Texas A&M

X-Factor: Devon Achane

For more on Texas A&M check out Aggies Wire

Colorado State at No. 6 Michigan

Sam Navarro-USA TODAY Sports

Game Time: 12:00 p.m. ET

Prediction: Michigan

X-Factor: Blake Corum

For more on Michigan check out Wolverines Wire

No. 22 Cincinnati at No. 23 Arkansas

Matt Pendleton-USA TODAY Sports

Game Time: 3:30 p.m. ET

Prediction: Arkansas

X-Factor: Jalen Catalon

For more on Arkansas check out Razorbacks Wire

North Dakota at Nebraska

Brendan Moran-USA TODAY Sports

Game Time: 3:30 p.m.

Prediction: Nebraska

X-Factor: Anthony Grant

For more on Nebraska check out Cornhuskers Wire

No. 12 Oregon vs No. 3 Georgia (Atlanta, Georgia)

Online Athens-USA TODAY Network

Game Time: 3:30 p.m. ET

Prediction: Georgia

X-Factor: Brock Bowers

For more on Oregon check out Ducks Wire

For more on the Dawgs check out UGA Wire

UTEP at No. 9 Oklahoma

Nathan J Fish/The Oklahoman / USA TODAY NETWORK

Game Time: 3:30 p.m. CT

Prediction: Oklahoma

X-Factor: Marvin Mims

For more on Oklahoma check out Sooners Wire

Rice at No. 15 USC

Kirby Lee-USA TODAY Sports

Game Time: 6:00 p.m. ET

Prediction: USC

X-Factor:  Jordan Addison

For more on USC check out Trojans Wire

No. 8 Utah at Florida

[Matt Pendleton/Gainesville Sun]

Game Time: 7:00 p.m.

Prediction: Florida

X-Factor: Ricky Pearsall

For more on Florida check out Gators Wire.

Mercer at Auburn

John Reed-USA TODAY Sports

Game Time: 7:00 p.m. ET

Prediction: Auburn

X-Factor: Tank Bigsby

Illinois State at Wisconsin

USA TODAY Network

Game Time: 7:00 p.m. ET

Prediction: Wisconsin

X-Factor: Braelon Allen

For more on Wisconsin check out Badgers Wire

Notre Dame at Ohio State

The Columbus Dispatch-USA TODAY Network

Game Time: 7:30 p.m. ET

Prediction: Ohio State

X-Factor: Jaxon Smith-Njigba

For more on Notre Dame check out Fighting Irish Wire

For more on Ohio State check out Buckeyes Wire

Utah State at No. 1 Alabama

Dale Zanine-USA TODAY Sports

Game Time: 7:30 p.m. ET

Prediction: Alabama

X-Factor: Jahmyr Gibbs

For more on Alabama check out Roll Tide Wire

Louisiana-Monroe at No. 18 Texas

Aaron E. Martinez/American-Statesman / USA TODAY NETWORK

Game Time: 8:00 p.m. ET

Prediction: Texas

X-Factor: Bijan Robinson

For more on Texas check out Longhorns Wire

Florida State vs LSU (New Orleans, Louisiana)

(AP Photo/Gerald Herbert)

Game Time: 7:30 p.m. ET (Sunday)

Prediction: LSU

X-Factor: Kayshon Boutte

For more on the Tigers check out LSU Wire

Clemson at Georgia Tech

Joseph Cress/Iowa City Press-Citizen / USA TODAY NETWORK

Game Time: 8:00 p.m. ET

Prediction: Clemson

X-Factor: DJ Uiagalelei

For more on the Tigers check out Clemson Wire

For more college football coverage follow @PatrickConnCFB on Twitter and join in on the conversation.

Story originally appeared on Fighting Irish Wire