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Super Bowl 58 picks against the spread: Will Chiefs or 49ers win big game?

Super Bowl 58 is finally here.

Patrick Mahomes and the Kansas City Chiefs will try to go back to back and win a second consecutive championship – and their third in the last five years – on Sunday in Las Vegas, while Christian McCaffrey and the San Francisco 49ers will try to win the franchise’s first title since the 1994 season (49ers -2 on bet365).

These two teams last met in Week 7 of the 2022 season, when Mahomes threw for three touchdowns in a 44-23 Chiefs win. That was a very different 49ers team, however, with QB Jimmy Garoppolo at the helm.

Mahomes won his first Super Bowl against the 49ers in February 2020, as Kansas City beat San Francisco, 31-20.

Bet $5 and get $150 in bonus bets or get a first bet safety net up to $1,000 on bet365.

The NFL Wires staff will be providing their picks against the spread throughout the season on Broncos Wire. All lines via bet365.

Follow along with bet365’s NFL coverage here.

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This article originally appeared on USA TODAY: Who wins Super Bowl 58? Picks against the spread for Chiefs-49ers tilt