NFL Week 6 picks, predictions: Who wins Seahawks-Bengals, Cowboys-Chargers, other games?
The NFL Week 6 schedule offers some enticing matchups.
Among them? The Seattle Seahawks and Cincinnati Bengals face off in a pivotal non-conference showdown.
The Indianapolis Colts and Jacksonville Jaguars play for the AFC South lead in another interesting matchup.
The Detroit Lions and Tampa Bay Buccaneers square off in an intriguing showdown between one-loss NFC teams.
And the Dallas Cowboys and Los Angeles Chargers end it all with a marquee Monday Night Football game.
Who will win each of those games, as well as the other NFL Week 6 games this week?
Check out our NFL Week 6 picks and NFL Week 6 predictions for every game on the Week 6 NFL schedule, which begins with the Denver Broncos at Kansas City Chiefs on Thursday Night Football and also includes the New York Giants at Buffalo Bills on Sunday Night Football.
The Green Bay Packers and Pittsburgh Steelers have byes this week.
All times MST. Click on each game for more predictions for that NFL Week 6 matchup.
NFL Week 6 picks: Broncos at Chiefs | Ravens at Titans | Commanders at Falcons | Vikings at Bears | Seahawks at Bengals | 49ers at Browns | Saints at Texans | Colts at Jaguars | Panthers at Dolphins | Patriots at Raiders | Lions at Buccaneers | Cardinals at Rams | Eagles at Jets | Giants at Bills | Cowboys at Chargers | Win probabilities | Odds | Schedule | Announcers | Power rankings
Thursday Night Football prediction
Denver Broncos at Kansas City Chiefs, 5:15 p.m., Amazon Prime Video (stream with Amazon Prime Video)
The Chiefs have benefitted from some controversial calls and no-calls in recent weeks. There won't be any controversy about their win over the Broncos.
Prediction: Chiefs 33, Broncos 17
NOTE: Every Sunday and Monday NFL game can be streamed locally on FUBO, click here for a free trial
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Sunday game in London prediction
Baltimore Ravens at Tennessee Titans, 6:30 a.m., NFL Network (stream with free trial from FUBO)
The Titans are interestingly 2-0 at home and 0-3 on the road. They are technically the home team for this game, but they will play it in London, not in Tennessee.
Prediction: Ravens 24, Titans 20
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Sunday early football games predictions
Washington Commanders at Atlanta Falcons, 10 a.m., CBS (stream with free trial from FUBO)
The Falcons have only scored 83 points this season, while they have given up 96. They are still 3-2. We think they will mover to 4-2 and 4-0 at home in this game.
Prediction: Falcons 21, Commanders 15
Minnesota Vikings at Chicago Bears, 10 a.m., FOX (stream with free trial from FUBO)
The winner of this game gets out of the NFC North cellar. The Bears looked good against the Commanders, but can they put together two solid weeks in a row? We have our doubts.
Prediction: Vikings 27, Bears 20
Seattle Seahawks at Cincinnati Bengals, 10 a.m., CBS (stream with free trial from FUBO)
This game got a lot more interesting after the Bengals' win over the Cardinals. It looked as if Joe Burrow, Ja'Marr Chase and the Bengals' offense got back on track.
Prediction: Bengals 24, Seahawks 23
San Francisco 49ers at Cleveland Browns, 10 a.m., FOX (stream with free trial from FUBO)
The Browns had their bye in Week 5, giving them an extra week to prepare for this game. It won't matter. The 49ers are just too good with Brock Purdy leading San Francisco's offense.
Prediction: 49ers 27, Browns 17
New Orleans Saints at Houston Texans, 10 a.m., FOX (stream with free trial from FUBO)
Did the Saints take a step forward with their shutout win over the Patriots? We think they did. New Orleans' defense will wreak some havoc on C.J. Stroud and company in this game.
Prediction: Saints 21, Texans 13
Indianapolis Colts at Jacksonville Jaguars, 10 a.m., CBS (stream with free trial from FUBO)
The winner of this game will lead the AFC South. We did not think the Colts would be in that position entering the season, but Trevor Lawrence and company will bring Indianapolis a little bit back to earth in this one.
Prediction: Jaguars 28, Colts 17
Carolina Panthers at Miami Dolphins, 10 a.m., CBS (stream with free trial from FUBO)
The Dolphins are a huge favorite in this game, and they should be. The Panthers don't have the offense, or the defense, to stay in this game against the Dolphins.
Prediction: Dolphins 31, Panthers 15
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Sunday late football games predictions
New England Patriots at Las Vegas Raiders, 1:05 p.m., CBS (stream with free trial from FUBO)
We don't have that much confidence in either team, but the Patriots didn't even put up a field goal against the Saints in Week 5.
Prediction: Raiders 21, Patriots 13
Detroit Lions at Tampa Bay Buccaneers, 1:25 p.m., FOX (stream with free trial from FUBO)
The Buccaneers had a bye week to rest up for this one. Baker Mayfield and Tampa Bay have impressed so far this season and will impress in a Week 6 thriller at home.
Prediction: Buccaneers 27, Lions 24
Arizona Cardinals at Los Angeles Rams, 1:25 p.m., FOX (stream with free trial from FUBO)
The Rams are 0-2 at home this season. They will likely be 1-2 after this game, one in which they will bring a lot of pressure on Josh Dobbs and the Cardinals' offense.
Prediction: Rams 28, Cardinals 20
Philadelphia Eagles at New York Jets, 1:25 p.m., FOX (stream with free trial from FUBO)
Something tells us that this game could be very interesting with Zach Wilson's improved play for the Jets. Just probably not interesting enough for the Jets to get a victory.
Prediction: Eagles 24, Jets 17
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Sunday Night Football prediction
New York Giants at Buffalo Bills, 5:20 p.m., NBC, Telemundo (stream with free trial from FUBO)
The Bills will return from a London loss to the Jaguars motivated to get back in the win column. That's bad news for the Giants.
Prediction: Bills 34, Giants 16
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Monday Night Football prediction
Dallas Cowboys at Los Angeles Chargers, 5:15 p.m., ABC, ESPN, ESPN Deportes (stream with free trial from FUBO)
The Cowboys have looked really impressive in their wins and really bad in their losses. They will need impress to beat the Chargers and we don't see them impressing enough.
Prediction: Chargers 30, Cowboys 24
More: What channel is Monday Night Football on? Here's who's playing and how to watch, stream
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: NFL Week 6 picks, predictions for every game on schedule this week
