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NFL Week 16 odds: Point spreads, moneylines, over/unders for betting on games

jeremy cluff, arizona republic
·3 min read
1

The NFL Week 16 schedule has some very interesting games, and some very interesting betting lines.

Who is the favorite in each game?

What do the betting odds say about each game?

The biggest point spreads of the week is the Buffalo Bills as a 13.5-point favorite against the Los Angeles Chargers and the Kansas City Chiefs as a 10-point favorite against the Las Vegas Raiders.

The smallest lines include the Miami Dolphins as a 1.5-point favorite against the Dallas Cowboys and the Indianapolis Colts as a 2-point favorite over the Atlanta Falcons.

Take a look at the point spread, moneyline and over/under for every game on the NFL Week 16 schedule, courtesy of BetMGM Sportsbook.

NFL Week 16 picks: Saints at Rams | Bengals at Steelers | Bills at Chargers | Colts at Falcons | Packers at Panthers | Browns at Texans | Lions at Vikings | Commanders at Jets | Seahawks at Titans | Jaguars at Buccaneers | Cardinals at Bears | Cowboys at Dolphins | Patriots at Broncos | Raiders at Chiefs | Giants at Eagles | Ravens at 49ers | Power rankings | Odds | Schedule

NFL Week 16 point spreads:

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NFL Week 16 moneylines:

  • New Orleans Saints (+165) at Los Angeles Rams (-200)

  • Cincinnati Bengals (-140) at Pittsburgh Steelers (+115)

  • Buffalo Bills (-900) at Los Angeles Chargers (+600)

  • Indianapolis Colts (-125) at Atlanta Falcons (+105)

  • Green Bay Packers (-210) at Carolina Panthers (+170)

  • Cleveland Browns (+115) at Houston Texans (-140)

  • Detroit Lions (-190) at Minnesota Vikings (+160)

  • Washington Commanders (+135) at New York Jets (-160)

  • Seattle Seahawks (-145) at Tennessee Titans (+120)

  • Jacksonville Jaguars (-140) at Tampa Bay Buccaneers (+120)

  • Arizona Cardinals (+165) at Chicago Bears (-200)

  • Dallas Cowboys (+105) at Miami Dolphins (-125)

  • New England Patriots (+200) at Denver Broncos (-250)

  • Las Vegas Raiders (+375) at Kansas City Chiefs (-500)

  • New York Giants (+400) at Philadelphia Eagles (-550)

  • Baltimore Ravens (+180) at San Francisco 49ers (-225)

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Gardner Minshew and the Indianapolis Colts are favored over the Atlanta Falcons in NFL Week 16 odds.
Gardner Minshew and the Indianapolis Colts are favored over the Atlanta Falcons in NFL Week 16 odds.

NFL Week 16 over/unders (point totals):

  • New Orleans Saints at Los Angeles Rams: 44.5

  • Cincinnati Bengals at Pittsburgh Steelers: 38.5

  • Buffalo Bills at Los Angeles Chargers: 42.5

  • Indianapolis Colts at Atlanta Falcons: 44.5

  • Green Bay Packers at Carolina Panthers: 36.5

  • Cleveland Browns at Houston Texans: 42

  • Detroit Lions at Minnesota Vikings: 46.5

  • Washington Commanders at New York Jets: 37.5

  • Seattle Seahawks at Tennessee Titans: 42.5

  • Jacksonville Jaguars at Tampa Bay Buccaneers: 44.5

  • Arizona Cardinals at Chicago Bears: 44.5

  • Dallas Cowboys at Miami Dolphins: 51

  • New England Patriots at Denver Broncos: 36.5

  • Las Vegas Raiders at Kansas City Chiefs: 43

  • New York Giants at Philadelphia Eagles: 43.5

  • Baltimore Ravens at San Francisco 49ers: 45.5

NOTE: NFL games can be streamed locally on FUBO, click here for a free trial

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: NFL Week 16 odds: Point spreads, moneylines, over/unders for betting