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NFL Week 15 odds: Moneylines, point spreads, over/under

The Philadelphia Eagles clinched a playoff spot last week, and were the first team to get their postseason ticket punched.

Week 15 opened with the San Francisco 49ers securing their own slot by winning the NFC West, beating the Seattle Seahawks 21-13. The 49ers were led yet again by Mr. Irrelevant Brock Purdy.

In a slate of Saturday games, the 10-3 Buffalo Bills also have a heated divisional matchup as they host the 8-5 Miami Dolphins and seek to further their position at the top of the AFC East. The Dolphins are the underdog as there is a 65% chance of snow.

On Sunday, Joe Burrow and the 9-4 Cincinnati Bengals take on Tom Brady and the 6-7 Tampa Bay Buccaneers in an interconference matchup with more playoff hopes on the line. The Bengals, who are on a five-game win streak, are favored to win.

Tom Brady yells before playing the New Orleans Saints.
Tom Brady yells before playing the New Orleans Saints.

No teams are on a bye week.

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Here's the odds for NFL Week 15, courtesy of Tipico Sportsbook.

NFL week 15 picks/predictions

NFL week 15 point spreads

  • San Francisco 49ers (-3.5) at Seattle Seahawks (+3.5)

  • Indianapolis Colts (+4) at Minnesota Vikings (-4)

  • Baltimore Ravens (+3) at Cleveland Browns (-3)

  • Miami Dolphins (+7) at Buffalo Bills (-7)

  • Atlanta Falcons (+4) at New Orleans Saints (-4)

  • Pittsburgh Steelers (+3) at Carolina Panthers (-3)

  • Philadelphia Eagles (-8.5) at Chicago Bears (+8.5)

  • Kansas City Chiefs (-14) at Houston Texans (+14)

  • Dallas Cowboys (-4.5) at Jacksonville Jaguars (+4.5)

  • Detroit Lions (+2) at New York Jets (-2)

  • Arizona Cardinals (+3) at Denver Broncos (-3)

  • New England Patriots (+1) at Las Vegas Raiders (-1)

  • Tennessee Titans (+3) at Los Angeles Chargers (-3)

  • Cincinnati Bengals (-3.5) at Tampa Bay Buccaneers (+3.5)

  • New York Giants (+4.5) at Washington Commanders (-4.5)

  • Los Angeles Rams (+7) at Green Bay Packers (-7)

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Brock Purdy (13) celebrates after scoring a touchdown during the 49ers' rout of the Buccaneers.
Brock Purdy (13) celebrates after scoring a touchdown during the 49ers' rout of the Buccaneers.

NFL week 15 moneylines

  • San Francisco 49ers (-180) at Seattle Seahawks (+155)

  • Indianapolis Colts (+170) at Minnesota Vikings (-200)

  • Baltimore Ravens (+125) at Cleveland Browns (-150)

  • Miami Dolphins (+270) at Buffalo Bills (-330)

  • Atlanta Falcons (+170) at New Orleans Saints (-200)

  • Pittsburgh Steelers (+130) at Carolina Panthers (-150)

  • Philadelphia Eagles (-400) at Chicago Bears (+320)

  • Kansas City Chiefs (-800) at Houston Texans (+550)

  • Dallas Cowboys (-200) at Jacksonville Jaguars (+170)

  • Detroit Lions (-105) at New York Jets (-125)

  • Arizona Cardinals (+135) at Denver Broncos (-155)

  • New England Patriots (-105) at Las Vegas Raiders (-115)

  • Tennessee Titans (+130) at Los Angeles Chargers (-155)

  • Cincinnati Bengals (-190) at Tampa Bay Buccaneers (+160)

  • New York Giants (+190) at Washington Commanders (-220)

  • Los Angeles Rams (+255) at Green Bay Packers (-310)

NFL week 15 over/under

  • San Francisco 49ers at Seattle Seahawks: 43

  • Indianapolis Colts at Minnesota Vikings: 47.5

  • Baltimore Ravens at Cleveland Browns: 38

  • Miami Dolphins at Buffalo Bills: 44.5

  • Atlanta Falcons at New Orleans Saints: 43.5

  • Pittsburgh Steelers at Carolina Panthers: 37.5

  • Philadelphia Eagles at Chicago Bears: 48

  • Kansas City Chiefs at Houston Texans: 49.5

  • Dallas Cowboys at Jacksonville Jaguars: 48

  • Detroit Lions at New York Jets: 44

  • Arizona Cardinals at Denver Broncos: 37

  • New England Patriots at Las Vegas Raiders: 44.5

  • Tennessee Titans at Los Angeles Chargers: 46.5

  • Cincinnati Bengals at Tampa Bay Buccaneers: 44.5

  • New York Giants at Washington Commanders: 40.5

  • Los Angeles Rams at Green Bay Packers: 39

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This article originally appeared on USA TODAY: NFL Week 15 betting odds