Las Vegas Raiders at Buffalo Bills picks, predictions, odds: Who wins NFL Week 2 game?
The Las Vegas Raiders and Buffalo Bills play on Sunday, Sept. 17 in an NFL Week 2 game at Highmark Stadium in Orchard Park, New York.
Which team will win the Week 2 NFL game?
Check out these NFL picks, predictions and odds for the game, which can be seen at 10 a.m. MST on CBS.
The Bills are a 9.5-point favorite over the Raiders in the game.
Buffalo is -450 on the moneyline, while Las Vegas is +350.
The over/under (point total) is set at 47.5.
The Raiders are coming of a 17-16 win against the Denver Broncos in their NFL Week 1 game.
The Bills lost their NFL Week 1 game against the New York Jets on Monday Night Football in overtime, 22-16.
More NFL Week 2 picks: Vikings at Eagles | Packers at Falcons | Raiders at Bills | Ravens at Bengals | Seahawks at Lions | Colts at Texans | Chiefs at Jaguars | Bears at Buccaneers | Chargers at Titans | Giants at Cardinals | 49ers at Rams | Jets at Cowboys | Commanders at Broncos | Dolphins at Patriots | Saints at Panthers | Browns at Steelers
The Arizona Republic: Bills 30, Raiders 20
Jeremy Cluff writes: "Jimmy Garoppolo did enough for the Raiders to beat the Broncos in Week 1, but the Buffalo Bills are a lot better than the Broncos."
NFL Week 2 schedule: Television channels, how to watch games
Bookies.com: Take the Raiders with the points against Bills
Bill Speros writes: "The Bills underperformed badly on the line last season, going 8-9-1 (including the playoffs), despite finishing 13-3 straight up as AFC East champs. Even worse, they were 3-6 as home favorites. This line is too steep. Just Cover, Baby!"
NFL Week 2 betting odds: Point spreads, moneylines, over/unders for games
Sports Betting Dime: Bills 32.4, Raiders 15.2
The site's formula predicts that the Bills will win the NFL Week 2 game against the Raiders.
NFL power rankings Week 2: Buccaneers, Browns, Packers, Rams, Lions surprise in upset wins
ESPN: Bills have a 73.6% chance to beat Raiders on Sunday
The site gives the Raiders a 26.2% shot at winning the Week 2 NFL game.
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CBS Sports: Odds favor taking the Raiders with the points in NFL Week 2 game vs. Bills
Tyler Sullivan writes: "The biggest line of Week 2 resides in Buffalo as the Bills are a 10-point favorite over Las Vegas. This was a spot where the Bills struggled last year, however, as they went 3-6 ATS as a home favorite in 2022. As for the Raiders, they were able to earn the SU win against the Broncos in Week 1 but did not cover. As a road 'dog last year, Josh McDaniels' team was 3-2 ATS."
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Las Vegas Raiders at Buffalo Bills picks, odds for NFL Week 2 game
