The over/under is 42.5 points.
The Giants finished 6-10 in 2020. Denver was 5-11.
Here are some trends to ponder should you find yourself wagering on the game, which is scheduled to kickoff at 4:25 p.m. on Sunday:
The Giants are….8-3 against the spread in their last 11 games as an underdog and the under is 7-0 in Giants last 7 games as an underdog.
The Broncos are….6-1 against the spread in their last 7 games on field turf and the under is 4-0 in Broncos last 4 games as a road favorite.