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Detroit Lions at New Orleans Saints picks, predictions, odds: Who wins NFL Week 13 game?

The Detroit Lions and New Orleans Saints play on Sunday, Dec. 3 at Caesars Superdome in a game on the NFL Week 13 schedule.

Which team will win the Week 13 NFL game?

Check out these NFL Week 13 picks and NFL Week 13 predictions for the game, which can be seen at 11 a.m. MST on FOX (stream with free trial from FUBO).

The Lions are a 3.5-point favorite over the Cowboys in NFL Week 13 odds for the game, courtesy of BetMGM Sportsbook.

Detroit is -185 on the moneyline, while New Orleans is +150.

The over/under (point total) is set at 44.5 points.

The Lions are coming off a 29-22 loss against the Green Bay Packers in their NFL Week 12 game.

The Saints are coming off a 24-15 loss against the Atlanta Falcons.

NFL Week 13 picks: Seahawks at Cowboys | Chargers at Patriots | Lions at Saints | Falcons at Jets | Cardinals at Steelers | Colts at Titans | Dolphins at Commanders | Broncos at Texans | Panthers at Buccaneers | Browns at Rams | 49ers at Eagles | Chiefs at Packers | Bengals at Jaguars | NFL power rankings | NFL odds | NFL schedule | NFL win probabilities | NFL playoff picture

The Arizona Republic: Lions 24, Saints 21

Jeremy Cluff writes: "The Lions are 4-1 away from home this season. We expect a bounce back game from Jared Goff in New Orleans against a struggling Saints team."

NFL Week 13 picks: Who wins Seahawks-Cowboys, Broncos-Texans, 49ers-Eagles, other games?

Bookies.com: Bet the Lions to cover vs. Saints

Bill Speros writes: "The Lions were caught napping on Thanksgiving by the Packers. The Saints won't have such luck, especially after Detroit's extended break. The Saints didn't score a touchdown in their 24-15 loss to the Falcons Sunday. The Lions offense should be able to regain its footing. The Lions will push to establish their running game. This number is a bit of discount, even with the hook."

NFL power rankings Week 13: Eagles, Ravens, Chiefs, 49ers, Cowboys among big winners

Sports Betting Dime: Lions 22.1, Saints 20.1

The site's formula predicts that the Lions will win the NFL Week 13 game against the Saints.

NFL Week 13 odds: Point spreads, moneylines, over/unders for betting on games this week

Will Alvin Kamara and the New Orleans Saints beat the Detroit Lions on Sunday? NFL Week 13 picks, predictions and odds weigh in on the game.
Will Alvin Kamara and the New Orleans Saints beat the Detroit Lions on Sunday? NFL Week 13 picks, predictions and odds weigh in on the game.

ESPN: Lions have a 56% chance to beat Saints on Sunday

The site gives the Saints a 43.6% shot at winning the Week 13 NFL game.

NFL Week 13 schedule: Television channels, how to watch, stream games

CBS Sports: Odds favor Lions vs. Saints in NFL Week 13

Tyler Sullivan writes: "Bettors expect a bounce-back from the Lions after being upset by the Packers on Thanksgiving. After opening up as a three-point road favorite against the Saints, Detroit is now laying 3.5 points. Dan Campbell's team has looked a bit vulnerable in recent weeks, but they have been a solid bet on the road. Away from Ford Field, the Lions are 4-1 ATS. That includes a 3-0 ATS mark as a road favorite. As for New Orleans, this is the first time this season that they'll be underdogs at the Superdome. This year, they've yet to cover a game at home, going 0-4 ATS.

NFL Week 13 predictions: ESPN matchup predictor's picks, win probabilities for this week

NFL playoff picture Week 13: Atlanta Falcons, Indianapolis Colts join postseason field

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STREAM THE GAME: Watch Lions at Saints live with FUBO (free trial)

WANNA BET? How to bet on NFL games in 2023

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Detroit Lions at New Orleans Saints picks, predictions for NFL Week 13