Detroit Lions at Los Angeles Chargers picks, predictions, odds: Who wins NFL Week 10 game?
The Detroit Lions and Los Angeles Chargers play on Sunday, Nov. 12 at SoFi Stadium in a game on the NFL Week 10 schedule.
Which team will win the Week 10 NFL game?
Check out these NFL Week 10 picks and NFL Week 10 predictions for the game, which can be seen at 2:05 p.m. MST on CBS (stream with free trial from FUBO).
The Lions are a 1.5-point favorite over the Chargers in NFL Week 10 odds for the game, courtesy of BetMGM Sportsbook.
Detroit is -115 on the moneyline, while Los Angeles is -105.
The over/under (point total) is set at 48.5 points.
The Lions are coming off a bye week.
The Chargers beat the New York Jets, 27-6 on Monday Night Football in the final game on the NFL Week 9 schedule.
NFL Week 10 picks: Panthers at Bears | Colts at Patriots | Browns at Ravens | Texans at Bengals | 49ers at Jaguars | Saints at Vikings | Packers at Steelers | Titans at Buccaneers | Falcons at Cardinals | Lions at Chargers | Giants at Cowboys | Commanders at Seahawks | Jets at Raiders | Broncos at Bills | Betting lines | How to watch on TV | NFL power rankings | Win probabilities | Playoff picture
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The Arizona Republic: Lions 30, Chargers 24
Jeremy Cluff writes: "The Lions had a bye week to get rested up for this game, while the Chargers had to play on Week 9's Monday Night Football game. Doesn't seem fair, does it?"
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Bookies.com: Take the Lions on the moneyline vs. Chargers
Bill Speros writes: "This line has shifted 3.5 points since it opened with LA as 2.5-point favorites. The Lions are now 1-point road favorites. No worry. Expect to see and hear plenty of Lions fans at SoFi. Detroit fans travel surprisingly well. And for the first time in decades, those Lions fans have reason to cheer in November. Lions QB Jared Goff returns to his home state, where he played college and pro ball with the Cal Golden Bears and LA Rams."
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Sports Betting Dime: Lions 28.5, Chargers 22.1
The site's formula predicts that the Lions will win the NFL Week 10 game against the Chargers.
NFL Week 10 predictions: ESPN matchup predictor's picks, win probabilities for this week
ESPN: Chargers have a 55.9% chance to beat Lions on Sunday
The site gives the Lions a 43.8% shot at winning the Week 10 NFL game.
NFL Week 10 odds: Point spreads, moneylines, over/unders for betting on games
CBS Sports: Odds favor Lions in NFL Week 10 vs. Chargers
Tyler Sullivan writes: "The Lions were on bye in Week 9, so they'll be by far the more rested team over the Chargers, who are playing on Monday night. Under Dan Campbell, the Lions are 6-2 ATS when they have the rest advantage. Under Chargers head coach Brandon Staley, L.A. is 5-6 ATS when they have the rest disadvantage. The Lions are 3-1 ATS on the road this year and the Detroit fans have traveled extremely well. When factoring in how previous fan bases have engulfed SoFi Stadium, this could feel like a home game for the Lions. The Chargers are 2-2 ATS at home this year."
NFL Week 10 schedule: Television channels, how to watch, stream games
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STREAM THE GAME: Watch Lions at Chargers live with FUBO (free trial)
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Detroit Lions at Los Angeles Chargers picks, odds for NFL Week 10 game
