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Arizona Cardinals at Chicago Bears picks, predictions, odds: Who wins NFL Week 16 game?

The Arizona Cardinals and Chicago Bears play on Sunday, Dec. 24 at Soldier Field in a game on the NFL Week 16 schedule.

Which team will win the Week 16 NFL game?

Check out these NFL Week 16 picks and NFL Week 16 predictions for the game, which can be seen at 2:25 p.m. MST on FOX (stream with free trial from FUBO).

The Bears are a 4.5-point favorite over the Cardinals in NFL Week 16 odds for the game, courtesy of BetMGM Sportsbook.

Chicago is -200 on the moneyline, while Arizona is +165.

The over/under (point total) is set at 44.5 points.

The Cardinals are coming off a 45-29 loss against the San Francisco 49ers in their NFL Week 15 game.

The Bears are coming off a 20-17 loss against the Cleveland Browns.

The Arizona Republic: Bears 27, Cardinals 23

Jeremy Cluff writes: "These teams are already looking ahead to next season. Will Kyler Murray and Justin Fields still be the QBs?"

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Bookies.com: Bet the Cardinals with the points vs. Bears

Bill Speros writes: "Bah. Humbug. The Bears have failed to cover in their past 12 games against teams that held a losing record. They are over-valued due to the size of the Chicago betting market."

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Sports Betting Dime: Bears 21.5, Cardinals 17.3

The site's formula predicts that the Bears will win the NFL Week 16 game against the Cardinals.

NFL Week 16 odds: Point spreads, moneylines, over/unders for betting on games

Will Kyler Murray and the Arizona Cardinals beat the Chicago Bears on Sunday? NFL Week 16 picks, predictions and odds for the game.
Will Kyler Murray and the Arizona Cardinals beat the Chicago Bears on Sunday? NFL Week 16 picks, predictions and odds for the game.

ESPN: Bears have a 62.1% chance to beat Cardinals on Sunday

The site gives the Cardinals a 37.6% shot at winning the Week 16 NFL game.

NFL Week 16 schedule: Television channels, how to watch, stream games this week

Pro Football Network: Take the Bears to beat the Cardinals in NFL Week 16

David Bearman writes: "Two teams playing out the string and figuring out what 2024 is going to look like. Both fought hard in losses in Week 14, with the Bears losing in the closing seconds. I lean Chicago here as they have been playing tough, but I’m not laying -4."

STREAM THE GAME: Watch Cardinals at Bears live with FUBO (free trial)

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Arizona Cardinals at Chicago Bears picks, predictions for NFL Week 16