New York Giants at Minnesota Vikings: Predictions, picks and odds for NFL Week 16 matchup
The Minnesota Vikings (11-3) are hosting a Winter Whiteout at home after winning the largest comeback in NFL history. Their opponent is the New York Giants (8-5-1) who are coming off a win of their own in a key divisional matchup.
Kirk Cousins and Justin Jefferson have secured their playoff berth and clinched the NFC North. They have won three of their last four games.
Brian Daboll has doubled the Giants' win count from last year in his first season and got the team back in the win column last week after a four-game drought.
Here's a look at the betting details and USA TODAY's NFL staff picks for the Giants vs. Vikings Week 16 game:
Giants at Vikings odds, moneyline and over/under
Spread: Vikings (-4.5)
Moneyline: Vikings (-210); Giants (+180)
Over/under: 48
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NFL Week 16 odds, predictions and picks
Jaguars at Jets | Falcons at Ravens | Lions at Panthers | Bills at Bears | Saints at Browns | Seahawks at Chiefs | Giants at Vikings | Bengals at Patriots | Texans at Titans | Commanders at 49ers | Eagles at Cowboys | Raiders at Steelers | Packers at Dolphins | Broncos at Rams | Buccaneers at Cardinals | Chargers at Colts
Safid Deen: Vikings 27, Giants 21
You don’t know which Vikings team is going to show up every game, to no fault but their own. But they still have too much offensive firepower behind Justin Jefferson and Dalvin Cook to play like they did last week against the Colts. The Giants will make it difficult, but Minnesota prevails at home.
Victoria Hernandez: Giants 24, Vikings 21
The Vikings have to be gassed after last week's historic comeback. Their starting center is banged up and their playoff spot is already locked in. The Giants have more to play for and Saquon Barkley is feeling the best he's felt in a while. Plus Kayvon Thibodeaux has been balling out.
Jaylon Thompson: Vikings 27, Giants 26
The Vikings will continue their magical run against the Giants. Minnesota finds a way to win each week and it will be no different on Saturday. Here is another caveat: the Vikings are 7-1 at home and have an outside chance at homefield advantage. It's enough motive for Captain Kirk to steer the ship once again to victory.
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This article originally appeared on USA TODAY: New York Giants at Minnesota Vikings: Game predictions, picks, odds