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Tampa Bay Buccaneers at Buffalo Bills: Predictions, picks and odds for NFL Week 8 game

NFL Week 8 will begin with a "Thursday Night Football" matchup between squads coming off disappointing divisional losses in the Tampa Bay Buccaneers (3-3) and Buffalo Bills (4-3).

With the top spot in the NFC South on the line, Tampa Bay was unable to capitalize on the near Bijan Robinson-less Atlanta Falcons in a home loss decided on a field goal. Desmond Ridder continued to make mistakes, but the Buccaneers couldn't capitalize. The offense is now declining, scoring only 19 points − including just one touchdown − in its past two games.

It's now panic time in Buffalo, as the Bills aren't playing like the Super Bowl contender they were expected to be at the beginning of the season. The lowly New England Patriots entered Sunday on a three-game losing streak and looked like one of the worst teams in the NFL, but the offense found a spark in a major upset of Buffalo. The Bills are in danger of falling to .500 against a pesky Tampa Bay team.

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Buffalo Bills tight end Dawson Knox (88) avoids a tackle from Tampa Bay Buccaneers linebacker Lavonte David (54) in the second half at Raymond James Stadium.
Buffalo Bills tight end Dawson Knox (88) avoids a tackle from Tampa Bay Buccaneers linebacker Lavonte David (54) in the second half at Raymond James Stadium.

Bills vs. Buccaneers odds, moneyline, over/under

The Bills are favorites to defeat the Buccaneers, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

  • Spread: Bills (-9.5)

  • Moneyline: Bills (-450); Buccaneers (+333)

  • Over/under: 43.5

Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

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NFL Week 8 odds, predictions and picks

Bills vs. Buccaneers | Panthers vs. Texans | Cowboys vs. Rams | Packers vs. Vikings | Colts vs. Saints | Dolphins vs. Patriots | Giants vs Jets | Steelers vs. Jaguars | Titans vs. Falcons | Commanders vs. Eagles | Seahawks vs. Browns | Cardinals vs. Ravens | Broncos vs. Chiefs | 49ers vs. Bengals | Chargers vs. Bears | Lions vs. Raiders

Lorenzo Reyes: Bills 24, Buccaneers 17

Buffalo, right now, is going through a rough patch and cannot be trusted to cover spreads this large. Josh Allen is turning the ball over with too great a frequency and the rushing game has been wildly inconsistent. On a short week, there’s not a lot of time to work out kinks. The Bucs, meanwhile, cannot afford to fall too far behind in the NFC South.

Tyler Dragon: Bills 28, Buccaneers 17

Both teams are coming off disappointing losses. The Bucs have lost two straight after starting 2-0. The quick turnaround favors the Bills playing at home. Buffalo has the NFL’s fifth-ranked offense and they average the third most points per game. Tampa Bay is near the bottom of the league in points per game.

Safid Deen: Bills 27, Bucs 23

The Bills and Buccaneers both need a bounce-back win Thursday night but give me Josh Allen over Baker Mayfield every single day of an eternity. It’ll be closer than we imagined, but I love Buffalo at home in this one.

Victoria Hernandez: Bills 23, Buccaneers 17

Both teams are coming off disappointing losses and, midway through the season, have proven to be inconsistent. The Bills are at home and have more to prove after an embarrassing loss to the lowly New England Patriots. Stefon Diggs is fourth in the league with 678 receiving yards and had a few impressive plays last week that should count for something in this matchup.

Jordan Mendoza: Bills 22, Buccaneers 16

Ever since that statement win against the Dolphins, it's been hard to trust Buffalo. The offense has been shaky and has a knack for playing down to lesser opponents. But a primetime game in Buffalo has proven it is tough to win for road opponents. The Bills squeak by, but don't cover this big point spread.

You can view the full list of USA TODAY's NFL expert predictions here.

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This article originally appeared on USA TODAY: Tampa Bay Buccaneers at Buffalo Bills: Game predictions, picks, odds