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Seattle Seahawks at Tennessee Titans picks, predictions, odds: Who wins NFL Week 16 game?

The Seattle Seahawks and Tennessee Titans play on Sunday, Dec. 24 at Nissan Stadium in a game on the NFL Week 16 schedule.

Which team will win the Week 16 NFL game?

Check out these NFL Week 16 picks and NFL Week 16 predictions for the game, which can be seen at 11 a.m. MST on CBS (stream with free trial from FUBO).

The Seahawks are a 2.5-point favorite over the Titans in NFL Week 16 odds for the game, courtesy of BetMGM Sportsbook.

Seattle is -145 on the moneyline, while Tennessee is +120.

The over/under (point total) is set at 42.5 points.

The Seahawks are coming off a 20-17 Monday Night Football win against the Philadelphia Eagles in NFL Week 15.

The Titans are coming off a 19-16 overtime loss against the Houston Texans.

NFL Week 16 picks: Saints at Rams | Bengals at Steelers | Bills at Chargers | Colts at Falcons | Packers at Panthers | Browns at Texans | Lions at Vikings | Commanders at Jets | Seahawks at Titans | Jaguars at Buccaneers | Cardinals at Bears | Cowboys at Dolphins | Patriots at Broncos | Raiders at Chiefs | Giants at Eagles | Ravens at 49ers | Power rankings | Odds | Schedule

The Arizona Republic: Titans 21, Seahawks 20

Jeremy Cluff writes: "The Titans are 1-6 on the road. Lucky for them, this game is at Nissan Stadium, where they are a respectable 4-3."

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Bookies.com: Bet the Titans with the points vs. Seahawks

Bill Speros writes: "The Seahawks played at home against Philly on Monday night. The Titans lost a heart-breaker in OT to the Texans in Week 15. There are three teams tied for the lead in the AFC South. The Titans are the fourth. Mike Vrabel is all but done as coach and may well be back in New England next season, where he helped the Patriots win 3 Super Bowls. The Titans have covered in 4 straight against the NFC West. They may well pull it off again here."

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Sports Betting Dime: Seahawks 19.5, Titans 17.6

The site's formula predicts that the Seahawks will win the NFL Week 16 game against the Titans.

NFL Week 16 odds: Point spreads, moneylines, over/unders for betting on games

ESPN: Seahawks have a 59.5% chance to beat Titans on Sunday

The site gives the Titans a 40.2% shot at winning the Week 16 NFL game.

NFL Week 16 schedule: Television channels, how to watch, stream games this week

Pro Football Network: Take Seahawks to cover vs. Titans in NFL Week 16

David Bearman writes: "I’d love this line more if Seattle wasn’t going west to east on short rest, which could screw with the players’ time clocks. These things happen from time to time, but they are still the better team here."

STREAM THE GAME: Watch Seahawks at Titans live with FUBO (free trial)

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Seattle Seahawks at Tennessee Titans picks, odds for NFL Week 16 game