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NCAA Tournament 2024: Sweet 16 odds, betting lines, spreads for every men's game

The NCAA Men's Tournament rolls into the Sweet 16, and the matchups have been decided following a weekend of nail-biters, upsets, and decisive victories, which reduced the field from 64 teams to just 16.

The top-seeded teams should not assume that they will have an easy path to victory from this point on. As we have seen in the past two rounds, the initial seeding of teams before the tournament is not a reliable indicator of their performance, as anything can happen once the game begins. The team that displays a winning mentality and backs it up with their actions will ultimately emerge victorious and advance to the Elite Eight.

Here are the current odds according to BetMGM for the remaining 16 teams and matchups as they vie for a bid into the Elite Eight.

Power rankings: Reseeding the Sweet 16: March Madness power rankings of the teams left in NCAA Tournament

Sweet 16 Bracket odds, betting line, spread

West Regional Sweet 16 matchups

Arizona vs. Clemson

No. 2 seeded Arizona Wildcats will take on No. 6 seeded Clemson Tigers in a Sweet 16 game on Thursday, March 28, at 7:09 p.m. ET, on CBS.

The Wildcats are favorites to defeat the Tigers in Thursday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Arizona (-7.5)

  • Moneylines: Arizona (-350); Clemson (+260)

  • Over/under: 152.5

North Carolina vs. Alabama

No. 1 seeded North Carolina Tar Heels will play No. 4 seeded Alabama Crimson Tide in a Sweet 16 game on Thursday, March 28, at 9:39 p.m., ET on CBS.

The Tar Heels are favorites to defeat the Crimson Tide in Thursday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: North Carolina (-4.5)

  • Moneylines: North Carolina(-175); Alabama (+150)

  • Over/under: 173.5

East Regional Sweet 16 matchups

UConn vs. San Diego State

No. 1 seeded UConn Huskies will face No. 5 seeded San Diego State Aztecs in a Sweet 16 game on Thursday, March 28 at 7:38 p.m., ET on TBS.

The Huskies are favorites to defeat the Aztecs in Thursday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: UConn (-10.5)

  • Moneylines: UConn (-650); San Diego State (+475)

  • Over/under: 136.5

Iowa State vs. Illinois

No. 2 seeded Iowa State Cyclones will face No. 5 seed Illinois Fighting Illini in a Sweet 16 game on Thursday, March 28 at 10:09 p.m., ET on TBS.

The Cyclones are favorites to defeat the Fighting Illini in Thursday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Iowa State (-1.5)

  • Moneylines: Iowa State (-135); Illinois (+110)

  • Over/under: 146.5

Midwest Regional Sweet 16 matchups

Purdue vs. Gonzaga

No. 1 seeded Purdue Boilermakers will face No. 5 seed Gonzaga Bulldogs in a Sweet 16 game on Friday, March 29 at 7:39 p.m., ET on TBS.

The Boilermakers are favorites to defeat the Bulldogs in Friday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Purdue (-5.5)

  • Moneylines: Purdue (-225); Gonzaga (+185)

  • Over/under: 154.5

Tennessee vs. Creighton

No. 2 seeded Tennessee Volunteers will face No. 3 seed Creighton Bluejays in a Sweet 16 game on Friday, March 29 at 10:09 p.m., ET on TBS.

The Volunteers are favorites to defeat the Bluejays in Friday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Tennessee (-2.5)

  • Moneylines: Tennessee (-125); Creighton (+125)

  • Over/under: 143.5

South Regional Sweet 16 matchups

Houston vs. Duke

No. 1 seeded Houston Cougars will face No. 4 seed Duke Blue Devils in a Sweet 16 game on Friday, March 29 at 9:39 p.m., ET on CBS.

The Cougars are favorites to defeat the Blue Devils in Friday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Houston (-4.5)

  • Moneylines: Houston (-190); Duke (+155)

  • Over/under: 139.5

Marquette vs. NC State

No. 2 seeded Marquette Golden Eagles will face No. 11 seed NC State Wolfpack in a Sweet 16 game on Friday, March 29 at 7:09 p.m., ET on CBS.

The Golden Eagles are favorites to defeat the Wolfpack in Friday's Sweet 16 March Madness matchup, according to the BetMGM college basketball odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds as of Tuesday.

  • Spread: Marquette (-6.5)

  • Moneylines: Marquette (-300); NC State (+230)

  • Over/under: 150.5

Elite Eight matchups

Pending the results of the Sweet 16 games, the Elite Eight matchups will be arranged as the following:

  • (1) Connecticut OR (5) San Diego State vs. (3) Illinois OR (2) Iowa State (East final)

  • (1) North Carolina OR (4) Alabama vs. (6) Clemson OR (2) Arizona (West final)

  • (1) Houston OR (4) Duke vs. (11) North Carolina State OR (2) Marquette (South final)

  • (1) Purdue OR (5) Gonzaga vs. (3) Creighton OR (2) Tennessee

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This article originally appeared on USA TODAY: Sweet 16 bracket odds, lines, spreads for every March Madness game