Los Angeles Chargers at New England Patriots picks, predictions: Who wins in NFL Week 13?

The Los Angeles Chargers and New England Patriots play on Sunday, Dec. 3 at Gillette Stadium in a game on the NFL Week 13 schedule.

Which team will win the Week 13 NFL game?

Check out these NFL Week 13 picks and NFL Week 13 predictions for the game, which can be seen at 11 a.m. MST on CBS (stream with free trial from FUBO).

The Chargers are a 5.5-point favorite over the Patriots in NFL Week 13 odds for the game, courtesy of BetMGM Sportsbook.

Los Angeles is -225 on the moneyline, while New England is +180.

The over/under (point total) is set at 41.5 points.

The Chargers are coming off a 20-10 loss against the Baltimore Ravens in their NFL Week 12 game.

The Patriots are coming off a 10-7 loss against the New York Giants.

NFL Week 13 picks: Seahawks at Cowboys | Chargers at Patriots | Lions at Saints | Falcons at Jets | Cardinals at Steelers | Colts at Titans | Dolphins at Commanders | Broncos at Texans | Panthers at Buccaneers | Browns at Rams | 49ers at Eagles | Chiefs at Packers | Bengals at Jaguars | NFL power rankings | NFL odds | NFL schedule | NFL win probabilities | NFL playoff picture

The Arizona Republic: Chargers 20, Patriots 16

Jeremy Cluff writes: "Could both of these coaches be coaching for their jobs? New England is 2-9. Los Angeles is 4-7. Both teams, and fan bases, had much higher expectations this season."

NFL Week 13 picks: Who wins Seahawks-Cowboys, Broncos-Texans, 49ers-Eagles, other games? Bet the under in Chargers vs. Patriots game

Bill Speros writes: "The Patriots have a nasty history of beating the Chargers at the worst times – for the Chargers. But those Patriots have been assigned to the dustbin of history. This line has spiked from 4 to 6.5 points in the past 48 hours ahead of Monday morning. The Patriots are in danger being unable to stop and/or keep up with the Chargers in this one. Even with the early East Coast start. Still, the Patriots are 8-3 on the under this season. Let's roll with that until further notice."

NFL power rankings Week 13: Eagles, Ravens, Chiefs, 49ers, Cowboys among big winners

Sports Betting Dime: Chargers 26.6, Patriots 15.4

The site's formula predicts that the Chargers will win the NFL Week 13 game against the Patriots.

NFL Week 13 odds: Point spreads, moneylines, over/unders for betting on games this week

Will Justin Herbert and the Los Angeles Chargers beat the New England Patriots on Sunday? NFL Week 13 picks, predictions and odds weigh in on the game.
Will Justin Herbert and the Los Angeles Chargers beat the New England Patriots on Sunday? NFL Week 13 picks, predictions and odds weigh in on the game.

ESPN: Chargers have a 65.9% chance to beat Patriots on Sunday

The site gives the Patriots a 33.8% shot at winning the Week 13 NFL game.

NFL Week 13 schedule: Television channels, how to watch, stream games

CBS Sports: Odds favor Chargers vs. Patriots in NFL Week 13

Tyler Sullivan writes: "The bottom has completely fallen out on the Patriots as they've dropped to 2-9 on the season and are arguably the worst team in the NFL. The quarterback situation continues to be in flux as Mac Jones was once again benched mid-game for Bailey Zappe. Now, they are getting 5.5 points as a home underdog to the Chargers and it wouldn't be surprising to see that number increase. This line initially opened at Chargers -4.5. L.A. hasn't been stellar this season either, but are leagues ahead of the Patriots, specifically at the quarterback position with Justin Herbert. The Chargers are 2-3 ATS on the road this season, which includes a 1-2 ATS record as a road favorite. Meanwhile, the Patriots are 1-4 ATS in Foxborough and 1-2 ATS as a home underdog."

NFL Week 13 predictions: ESPN matchup predictor's picks, win probabilities for this week

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STREAM THE GAME: Watch Chargers at Patriots live with FUBO (free trial)

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This article originally appeared on Arizona Republic: Los Angeles Chargers at New England Patriots picks for NFL Week 13