Kansas City Chiefs at Jacksonville Jaguars predictions, odds: Who wins NFL Week 2 game?
The Kansas City Chiefs and Jacksonville Jaguars play on Sunday, Sept. 17 in an NFL Week 2 game at EverBank Stadium in Jacksonville.
Which team will win the Week 2 NFL game?
Check out these NFL picks, predictions and odds for the game, which can be seen at 10 a.m. MST on CBS.
The Chiefs are a 2.5-point favorite over the Jaguars in the game.
Kansas City is -155 on the moneyline, while Jacksonville is +130.
The over/under (point total) is set at 50.5.
The Chiefs are coming of a 21-20 loss against the Detroit Lions in their NFL Week 1 game.
The Jaguars are coming off a 31-21 win against the Indianapolis Colts in their season opener.
More NFL Week 2 picks: Vikings at Eagles | Packers at Falcons | Raiders at Bills | Ravens at Bengals | Seahawks at Lions | Colts at Texans | Chiefs at Jaguars | Bears at Buccaneers | Chargers at Titans | Giants at Cardinals | 49ers at Rams | Jets at Cowboys | Commanders at Broncos | Dolphins at Patriots | Saints at Panthers | Browns at Steelers
The Arizona Republic: Chiefs 27, Jaguars 24
Jeremy Cluff writes: "The Chiefs can't lose twice in a row to start the season, can they? We don't think they will, but this will be close."
NFL Week 2 schedule: Television channels, how to watch games
Bookies.com: Take the Jaguars on the moneyline vs. Chiefs in NFL Week 2
Bill Speros writes: "The difference here might be the weather. This 1 p.m. start in North Florida in mid-September calls for rain and humid weather with temperatures in the mid 80s as Hurricane Lee rages 300 miles to the East. Will Patrick Mahomes and the defending Super Bowl champions begin the season 0-2? Kadarius Toney played his college ball at Florida so maybe he'll hold on to the ball this time. The Jaguars (+3) were 5-0 ATS as home cats, er dogs, last season. We like them to win outright. Duuuuuuvallll."
NFL Week 2 betting odds: Point spreads, moneylines, over/unders for games
Sports Betting Dime: Chiefs 27.6, Jaguars 21.6
The site's formula predicts that the Chiefs will win the NFL Week 2 game against the Jaguars.
NFL power rankings Week 2: Buccaneers, Browns, Packers, Rams, Lions surprise in upset wins
ESPN: Chiefs have a 61.1% chance to beat Jaguars on Sunday
The site gives the Jaguars a 38.6% shot at winning the Week 2 NFL game.
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CBS Sports: Odds favor Jaguars in NFL Week 2 game vs. Chiefs
Tyler Sullivan writes: "Jacksonville had some issues containing Colts rookie QB Anthony Richardson but was able to muster the Week 1 win and cover in the process. The Jaguars look to go 2-0 SU and ATS when they host the defending Super Bowl champions, who are looking to rebound following an opening loss to Detroit. Kansas City was 4-5 ATS on the road a season ago while the Jaguars were 5-3 ATS at home in 2022."
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Kansas City Chiefs at Jacksonville Jaguars picks, odds for NFL Week 2
