Nelson (18-5-1 MMA, 9-5 UFC) faces Rodriguez (17-3 MMA, 7-2 UFC) on March 18 at The O2 in London, the promotion announced Monday on social media.
Nelson returned from a two-and-a-half year layoff last March when he defeated Takashi Sato in his first bout of a new multifight deal. The win snapped a two-fight losing skid.
After winning four straight over the likes of Kevin Lee and Li Jingliang, Rodriguez saw his winning streak snapped this past November when he was submitted by Neil Magny at UFC Fight Night 214.
Leon Edwards vs. Kamaru Usman title fight trilogy bout set for UFC 286 in London
Rafael Fiziev gets wish, meets Justin Gaethje at UFC 286 in London
Lerone Murphy vs. Nathaniel Wood headed to UFC 286 in London
With the addition, the UFC 286 lineup includes:
Champ Leon Edwards vs. Kamaru Usman – for welterweight title
Rafael Fiziev vs. Justin Gaethje
Roman Dolidze vs. Marvin Vettori
Gunnar Nelson vs. Daniel Rodriguez
Luana Carolina vs. Joanne Wood
Malcolm Gordon vs. Jake Hadley
Jennifer Maia vs. Casey O’Neill
Jai Herbert vs. Ludovit Klein
Lerone Murphy vs. Nathaniel Wood
Chris Duncan vs. Michal Figlak
Veronica Macedo vs. Juliana Miller
For more on the card, visit MMA Junkie’s event hub for UFC 286.