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Cleveland Browns at Indianapolis Colts picks, predictions, odds: Who wins NFL Week 7 game?

The Cleveland Browns and Indianapolis Colts play on Sunday, Oct. 22 at Lucas Oil Stadium in a game on the NFL Week 7 schedule.

Which team will win the Week 7 NFL game?

Check out these NFL Week 7 picks and NFL Week 7 predictions for the game, which can be seen at 10 a.m. MST on CBS (stream with free trial from FUBO).

The Browns are a 1.5-point favorite over the Colts in NFL Week 7 odds for the game.

Cleveland is -125 on the moneyline, while Indianapolis is +105.

The over/under (point total) is set at 39 points.

The Browns are coming off a 19-17 win against the San Francisco 49ers in their NFL Week 6 game.

The Colts are coming off a 37-20 loss against the Jacksonville Jaguars.

NFL Week 7 picks: Jaguars at Saints | Lions at Ravens | Raiders at Bears | Browns at Colts | Bills at Patriots | Commanders at Giants | Falcons at Buccaneers | Steelers at Rams | Cardinals at Seahawks | Packers at Broncos | Chargers at Chiefs | Dolphins at Eagles | 49ers at Vikings | Lines | TV | Power rankings

The Arizona Republic: Browns 24, Colts 17

Jeremy Cluff writes: "The Browns made a statement with their win over the 49ers. Will they build off of it in NFL Week 7? Yes, they will. Their defense will once again be the difference."

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Bookies.com: Take the Browns on the moneyline vs. Colts

Bill Speros writes: "Gardner Minshew gets the call for the Colts, likely against P.J. Walker. With Walker at QB, the Browns upended the 49ers. Cleveland's defense should deliver on the road this week. The Colts have lost seven of their last eight home games."

NFL power rankings Week 7: Dolphins, Chiefs, Eagles, 49ers or Lions best team right now?

Sports Betting Dime: Browns 19, Colts 13.6

The site's formula predicts that the Browns will win the NFL Week 7 game against the Colts.

NFL Week 7 odds: Point spreads, moneylines, over/unders for betting on games this week

NFL Week 7 picks and predictions weigh in on Sunday's Cleveland Browns vs. Indianapolis Colts game.
NFL Week 7 picks and predictions weigh in on Sunday's Cleveland Browns vs. Indianapolis Colts game.

ESPN: Browns have a 59.9% chance to beat Colts on Sunday

The site gives the Colts a 39.7% shot at winning the Week 7 NFL game.

NFL Week 7 schedule: Television channels, how to watch, how to stream games

CBS Sports: Odds favor the under in Browns vs. Colts game

Tyler Sullivan writes: The Browns enjoyed one of the biggest upsets of Week 6 by taking down the previously unbeaten 49ers with P.J. Walker under center. Of course, it remains to be seen if Deshaun Watson will be healthy enough to make his return for this game or if Walker will get another start following that impressive win. Even with that QB situation still in flux, Cleveland is a 2-point road favorite over Indy, who'll again be starting Gardner Minshew for the injured Anthony Richardson. The Colts fell to Jacksonville on Sunday to drop to 3-3 on the year. Indy is 1-2 ATS at home this season while the Browns were unable to cover their lone road game of the year in Week 2 against Pittsburgh. Scoring isn't expected in this contest with a total set at 39, the lowest of the Week 7 slate currently.

STREAM THE GAME: Watch Browns at Colts live with FUBO (free trial)

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Cleveland Browns at Indianapolis Colts picks, odds for NFL Week 7