Arizona Cardinals at Los Angeles Rams: Predictions, picks and odds for NFL Week 10 matchup
Two teams looking to find their footing in the NFC West, Kyler Murray leads the Arizona Cardinals (3-6) into Los Angeles to face Matthew Stafford and the Rams (3-5).
The Rams have historically dominated the Cardinals, which could give Los Angeles an edge in this matchup. Still, both teams are desperate to keep pace with the division-leading Seattle Seahawks as well as the San Francisco 49ers. Who will come out on top? The game is scheduled to kick off Sunday at 4:25 p.m. ET from SoFi Stadium.
Here's a look at the betting details and USA TODAY's NFL staff picks for the Cardinals vs. Rams Week 10 game:
Cardinals at Rams odds, moneyline and over/under
Spread: Rams (-3)
Moneyline: Rams (-145); Cardinals (+125)
Over/under: 40.5
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NFL Week 10 odds, predictions and picks
Falcons vs. Panthers | Seahawks vs. Buccaneers | Browns vs. Dolphins | Broncos vs. Titans | Texans vs. Giants | Lions vs. Bears | Vikings vs. Bills | Saints vs. Steelers | Jaguars vs. Chiefs | Colts vs. Raiders | Cowboys vs. Packers | Cardinals vs. Rams | Chargers vs. 49ers | Commanders at Eagles
Lorenzo Reyes: Rams 17, Cardinals 16
These are both unreliable teams loaded with talent that has underwhelmed. I think there are better plays out there, but I don’t have enough confidence in the Rams right now to see them clearing anything above a field goal.
Safid Deen: Rams 28, Cardinals 24
The Rams' offense is still searching for help beyond Cooper Kupp. But the Rams' defense couldn’t keep Tom Brady and the Bucs out of the end zone in the final minute last week. That will motivate them against Murray, DeAndre Hopkins and the Cardinals, who have found more ways to lose than win.
Lance Pugmire: Rams 27, Cardinals 21
The champions make a last stand against their division rival. If not, that’s a mighty fall from a Super Bowl ring to a playoff absence.
Jarrett Bell: Rams 24, Cardinals 20
Nate Davis: Cardinals 23, Rams 20
Tyler Dragon: Rams 24, Cardinals 20
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This article originally appeared on USA TODAY: Arizona Cardinals at Los Angeles Rams: Game predictions, picks, odds