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Washington Commanders at Denver Broncos predictions, odds: Who wins NFL Week 2 game?

The Washington Commanders and Denver Broncos play on Sunday, Sept. 17 in an NFL Week 2 game at Empower Field at Mile High in Denver.

Which team will win the Week 2 NFL game?

Check out these NFL picks, predictions and odds for the game, which can be seen at 1:25 p.m. MST on CBS.

The Broncos are a 3.5-point favorite over the Commanders in the game.

Denver is -200 on the moneyline, while Washington is +165.

The over/under (point total) is set at 40.5.

The Commanders are coming of a 20-16 win against the Arizona Cardinals in their NFL Week 1 game.

The Broncos are coming off a 17-16 loss against the Las Vegas Raiders in their season opener.

More NFL Week 2 picks: Vikings at Eagles | Packers at Falcons | Raiders at Bills | Ravens at Bengals | Seahawks at Lions | Colts at Texans | Chiefs at Jaguars | Bears at Buccaneers | Chargers at Titans | Giants at Cardinals | 49ers at Rams | Jets at Cowboys | Commanders at Broncos | Dolphins at Patriots | Saints at Panthers | Browns at Steelers

The Arizona Republic: Commanders 20, Broncos 17

Jeremy Cluff writes: "The Commanders' defense can cause Russell Wilson and the Broncos fits. We think they will have the Denver QB on his heels throughout this game."

NFL Week 2 schedule: Television channels, how to watch games

Bookies.com: Take the Broncos to cover vs. Commanders in NFL Week 2

Bill Speros writes: "The Commanders have made second-year passer Sam Howell their QB of the present and future. Howell had just one start last season, a win in a meaningless game against Dallas in Week 18. Howell will be tested by the Broncos defense and the Mile High crowd. Don't horse around. Back the Broncos at home."

NFL Week 2 betting odds: Point spreads, moneylines, over/unders for games

Will Russell Wilson and the Denver Broncos beat the Washington Commanders in NFL Week 2?
Will Russell Wilson and the Denver Broncos beat the Washington Commanders in NFL Week 2?

Sports Betting Dime: Commanders 13.8, Broncos 8.5

The site's formula predicts that the Commanders will win the NFL Week 2 game against the Broncos.

NFL power rankings Week 2: Buccaneers, Browns, Packers, Rams, Lions surprise in upset wins

ESPN: Broncos have a 66.1% chance to beat Commanders on Sunday

The site gives the Commanders a 33.6% shot at winning the Week 2 NFL game.

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CBS Sports: Odds favor Broncos in NFL Week 2 game vs. Commanders

Tyler Sullivan writes: "The Commanders were able to notch a win in Week 1 but did fail to cover against Arizona. Meanwhile, Denver couldn't get the victory over Las Vegas but was able to stay within the number. Last season, the Broncos were 3-5 ATS at home."

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Washington Commanders at Denver Broncos picks, odds for NFL Week 2