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Chiefs vs. Bills preview: Prediction, odds, how to watch divisional round game

For the third time in four years, the Buffalo Bills and Kansas City Chiefs will meet in the postseason.

Since Patrick Mahomes and Josh Allen took over as the starting quarterback for their respective teams in 2018, the Bills and Chiefs have met six times. Buffalo has won three out of four regular season clashes, including a 20-17 victory in early December, but Kansas City has won both playoff matchups.

This year, Mahomes travels for a playoff game for the first time in his career. For the Chiefs, it's their first road playoff game since 2015.

The Bills will be looking to make their home-field advantage count to push them into the AFC Championship for the first time since January 2021.

Here's everything to know about this clash of AFC titans.

NFL QB confidence meter: Any playoff passers to trust beyond Patrick Mahomes?

Chiefs vs. Bills predictions

The Arizona Republic: Bills 24, Chiefs 23

Jeremy Cluff writes, "Buffalo won a close game against the Chiefs in Kansas City in Week 14, we predict they will win another close game against the Chiefs in Buffalo in the Divisional Round, with the Bills' defense coming up big late."

Sporting News: Bills 28, Chiefs 24

Bill Bender writes, "If [Josh] Allen avoids field-changing interceptions, then Buffalo should be able to feed off the home crowd in the elements. Allen has played well in the last two playoff losses against the Chiefs. This time, the Bills' defense ends Kansas City's hopes for a repeat by forcing a late turnover."

ESPN: Bills slight favorites to win at home

ESPN Analytics give the Bills a 56.6% chance to win at home and advance to the AFC Championship. The same model gives the Chiefs a 43.4% chance to take the road win and move to 3-0 against the Bills in their last three playoff meetings.

Chiefs vs. Bills odds, spread and lines

The Bills are favorites to defeat the Chiefs, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

All odds as of Saturday.

  • Spread: Bills (-2.5)

  • Moneyline: Bills (-145); Chiefs (+120)

  • Over/under: 45.5

Chiefs vs. Bills injury updates

Kansas City Chiefs

PLAYER

POSITION

INJURY

STATUS

Kadarius Toney

WR

Hip

Questionable for the Divisional Playoffs at Buffalo

Justyn Ross

WR

Hamstring

Questionable for the Divisional Playoffs at Buffalo

Derrick Nnadi

NT

Triceps

Out for the Divisional Playoffs at Buffalo

Wanya Morris

OT

Concussion

Out for the Divisional Playoffs at Buffalo

Jerick McKinnon

RB

Sports Hernia

Injured Reserve

Nazeeh Johnson

SAF

Knee

Injured Reserve

Cam Jones

LB

Chest

Injured Reserve

Jody Fortson

TE

Shoulder

Injured Reserve

Skyy Moore

WR

Knee

Injured Reserve

Prince Tega Wanogho

OT

Quadriceps

Injured Reserve

Bryan Cook

FS

Ankle

Injured Reserve

Buffalo Bills

Taylor Rapp S

QUESTIONABLE

Terrel Bernard LB

QUESTIONABLE

Christian Benford CB

QUESTIONABLE

Tyrel Dodson LB

QUESTIONABLE

Rasul Douglas CB

QUESTIONABLE

How to watch Packers vs. Cowboys: TV, streaming and schedule

When: Sunday, Jan. 21, 6:30 p.m. ET

Where: Highmark Stadium, Orchard Park, N.Y.

Cable TV: CBS

Streaming: Paramount+; YouTube TV; Sling; FuboTV

How to watch: Catch all NFL playoff action with a Fubo subscription

This article originally appeared on USA TODAY: Chiefs vs. Bills: Predictions, odds and how to watch divisional round