May 21
Jon Lester yielded six runs -- five earned -- in six innings Monday against the White Sox to take his first loss of the season.
Advice: Lester, who entered 6-0, has always had problems with the White Sox. He's now 4-5 with a 5.43 ERA in 10 career starts against the team. He's 87-44 with a 3.64 ERA against everyone else.