San Francisco 49ers
| 1-2
NaN/NaN
| Date | Home/Away | Opponent | Status | Score |
|---|---|---|---|---|
| (Preseason) | vs |  Dallas | W | 24 - 21 |
| (Preseason) | @ | Houston | L | 16 - 13 |
| (Preseason) | @ | Indianapolis | L | 23 - 17 |
| (Preseason) | vs | LA Chargers | L | 23 - 21 |
| @ | Minnesota | L | 24 - 16 | |
| vs | Detroit | W | 30 - 27 | |
| @ | Kansas City | L | 38 - 27 |
| Date | Home/Away | Opponent | Time |
|---|---|---|---|
| @ | LA Chargers | CBS | |
| vs | Arizona | FOX | |
| @ | Green Bay | ESPN | |
| vs | LA Rams | NBC | |
| @ | Arizona | FOX | |
| vs | Oakland | FOX, NFLN | |
| vs | NY Giants | ESPN | |
| Bye Week | |||
| @ | Tampa Bay | FOX | |
| @ | Seattle | NBC | |
| vs | Denver | CBS | |
| vs | Seattle | FOX | |
| vs | Chicago | FOX | |
| @ | LA Rams | FOX |