| | C | Activated (The Pittsburgh Pirates activated C Yasmani Grandal from the 10-day injured list.) |
| | C | Sent to Minors (The Pittsburgh Pirates optioned C Henry Davis to the minors.) |
| | SS | Traded (The New York Yankees traded INF Keiner Delgado to the Pittsburgh Pirates.) From |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates recalled SP Kyle Nicholas from the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Ryder Ryan to the minors.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates recalled RHP Quinn Priester from the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned LHP Jose Hernandez to the minors.) |
| | 2B | Sent to Minors (The Pittsburgh Pirates activated INF Ji Hwan Bae from the 10-day injured list and optioned to the minors.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates recalled SP Ryder Ryan from the minors.) |
| | P | Placed on 15-Day IL (The Pittsburgh Pirates placed SP Marco Gonzales on the 15-day injured list.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Colin Holderman from the 15-day injured list.) |
| | P | Sent to Minors (The Pittsburgh Pirates activated RHP Carmen Mlodzinski from the minors and optioned him to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RP Ryder Ryan to the minors.) |
| | P | Placed on 15-Day IL (The Pittsburgh Pirates placed RP Ryan Borucki on the 15-Day Injury List with left triceps inflammation.) |
| | | Traded (The Kansas City Royals traded RP Connor Oliver to the Pittsburgh Pirates.) From |
| | P | Traded (The Pittsburgh Pirates traded RP Colin Selby to the Kansas City Royals.) To |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates recalled RP Jose Hernandez from the minors.) |
| | C | Activated (The Pittsburgh Pirates activated C Joey Bart.) |
| | C | Placed on 10-Day IL (The Pittsburgh Pirates placed C Jason Delay on the 10-day injured list.) |
| | | Traded (The San Diego Padres traded SS Kervin Pichardo to the Pittsburgh Pirates.) From |
| | P | Traded (The Pittsburgh Pirates traded RHP Austin Strickland to the San Francisco Giants. ) To |
| | C | Traded (The San Francisco Giants traded C Joey Bart to the Pittsburgh Pirates.) From |
| | P | Designated for Assignment (The Pittsburgh Pirates Designated RHP Colin Selby for assignment.) |
| | P | Traded (The Pittsburgh Pirates traded LHP Jackson Wolf to the San Diego Padres.) To |
| | RF | Sent to Minors (The Pittsburgh Pirates sent OF Canaan Smith-Njigba outright to the minors.) |
| | C | Declared Free Agency (C Alí Sánchez elected free agency.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RP Jose Hernandez to the minors.) |
| | P | Activated (The Pittsburgh Pirates activated RP Roansy Contreras from the paternity leave list.) |
| | C | Sent to Minors (The Pittsburgh Pirates sent C Alí Sánchez outright to the minors.) |
| | P | Traded (The Pittsburgh Pirates traded RHP JT Brubaker to the New York Yankees.) To |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Colin Holderman to the minors on a rehab assignment.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates recalled LHP Jose Hernandez from the minors.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates selected the contract of RHP Hunter Stratton from the minors.) |
| | C | Placed on 10-Day IL (The Pittsburgh Pirates placed C Yasmani Grandal on the 10-day injured list.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates selected the contract of RHP Ryder Ryan from the minors.) |
| | P | Designated for Assignment (The Pittsburgh Pirates designated LHP Jackson Wolf for assignment.) |
| | RF | Designated for Assignment (The Pittsburgh Pirates designated OF Canaan Smith-Njigba for assignment.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates selected the contract of RHP Jared Jones from the minors.) |
| | P | Placed on Paternity Leave List (The Pittsburgh Pirates placed RHP Roansy Contreras on the Paternity Leave list.) |
| | P | Placed on 15-Day IL (The Pittsburgh Pirates placed RHP Colin Holderman on the 15-day injured list.) |
| | 2B | Placed on 10-Day IL (The Pittsburgh Pirates placed INF Ji Hwan Bae on the 10-day injured list.) |
| | P | Placed on 15-Day IL (The Pittsburgh Pirates placed RHP Carmen Mlodzinski on the 15-day injured list.) |
| | C | Declared Free Agency (The Pittsburgh Pirates designated C Alí Sánchez for assignment.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Wily Peralta to the minors.) |
| | 1B | Sent to Minors (The Pittsburgh Pirates sent INF Jake Lamb to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent LHP Eric Lauer to the minors.) |
| | LF | Sent to Minors (The Pittsburgh Pirates sent OF Billy McKinney to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Brent Honeywell to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Hunter Stratton to the minors.) |
| | CF | Sent to Minors (The Pittsburgh Pirates sent OF Gilberto Celestino to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Domingo Germán to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Jared Jones to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Ryder Ryan to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Quinn Priester to the minors.) |
| | SS | Sent to Minors (The Pittsburgh Pirates optioned INF Liover Peguero to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned LHP Jose Hernandez to the minors.) |
| | P | Released (The Pittsburgh Pirates released RHP Chase Anderson.) |
| | RF | Sent to Minors (The Pittsburgh Pirates optioned OF Joshua Palacios to the minors.) |
| | 2B | Sent to Minors (The Pittsburgh Pirates optioned INF Nick Gonzales to the minors.) |
| | C | Sent to Minors (The Pittsburgh Pirates sent C Carter Bins to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Kyle Nicolas to the minors.) |
| | CF | Sent to Minors (The Pittsburgh Pirates sent OF Matt Gorski to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Paul Skenes to the minors.) |
| | SS | Sent to Minors (The Pittsburgh Pirates sent INF Sergio Alcántara to the minors.) |
| | 3B | Sent to Minors (The Pittsburgh Pirates sent INF Joe Perez to the minors.) |
| | P | Placed on 60-Day IL (The Pittsburgh Pirates placed RHP Dauri Moreta on the 60-day injured list.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Domingo Germán to a minor league contract with an invitation to spring training.) |
| | CF | Signed (The Pittsburgh Pirates signed RF Michael A. Taylor.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Jack Brannigan to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Colin Selby to the minors.) |
| | 2B | Sent to Minors (The Pittsburgh Pirates sent INF Termarr Johnson to the minors.) |
| | RF | Sent to Minors (The Pittsburgh Pirates optioned OF Canaan Smith-Njigba to the minors.) |
| | SS | Sent to Minors (The Pittsburgh Pirates optioned INF Tsung-Che Cheng to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Braxton Ashcraft to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent LHP Michael Plassmeyer to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned RHP Mike Burrows to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Ben Heller to the minors.) |
| | C | Sent to Minors (The Pittsburgh Pirates sent C Abrahan Gutierrez to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Sean Sullivan to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Connor Sadzeck to the minors.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Eric Lauer to a minor league contract.) |
| | SS | Sent to Minors (The Pittsburgh Pirates sent INF Andrés Alvarez to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent LHP Anthony Solometo to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates optioned LHP Jackson Wolf to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Bubba Chandler to the minors.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent RHP Thomas Harrington to the minors.) |
| | LF | Signed (The Pittsburgh Pirates signed OF Dustin Peterson to a minor league contract.) |
| | RF | Claimed on Unconditional Release Waivers (The Pittsburgh Pirates claimed OF Canaan Smith-Njigba off waivers from the Seattle Mariners.) |
| | P | Placed on 60-Day IL (The Pittsburgh Pirates placed RHP JT Brubaker on the 60-day injured list.) |
| | C | Placed on 60-Day IL (The Pittsburgh Pirates placed C Endy Rodríguez on the 60-day injured list.) |
| | P | Placed on 60-Day IL (The Pittsburgh Pirates placed RHP Johan Oviedo on the 60-day injured list.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Josh Fleming.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Connor Sadzeck to spring training.) |
| | C | Signed (The Pittsburgh Pirates signed C Yasmani Grandal.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Connor Sadzeck to a minor league contract.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Kade McClure to a minor league contract.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Connor Sadzeck to a minor league contract.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Kade McClure to a minor league contract.) |
| | RF | Waived (The Pittsburgh Pirates waived OF Canaan Smith-Njigba.) |
| | RF | Designated for Assignment (The Pittsburgh Pirates designated OF Canaan Smith-Njigba for assignment.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited LHP Anthony Solometo to spring training.) |
| | CF | Non-roster Invitee (The Pittsburgh Pirates invited OF Matt Gorski to spring training.) |
| | 2B | Non-roster Invitee (The Pittsburgh Pirates invited INF Termarr Johnson to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Bubba Chandler to spring training.) |
| | SS | Non-roster Invitee (The Pittsburgh Pirates invited INF Andrés Alvarez to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Paul Skenes to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Sean Sullivan to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Jared Jones to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Thomas Harrington to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Jack Brannigan to spring training.) |
| | C | Non-roster Invitee (The Pittsburgh Pirates invited C Carter Bins to spring training.) |
| | 3B | Non-roster Invitee (The Pittsburgh Pirates invited INF Joe Perez to spring training.) |
| | C | Non-roster Invitee (The Pittsburgh Pirates invited C Abrahan Gutierrez to spring training.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Aroldis Chapman.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Brady Feigl to a minor league contract.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited RHP Ben Heller to spring training.) |
| | SS | Non-roster Invitee (The Pittsburgh Pirates invited INF Sergio Alcántara to spring training.) |
| | P | Non-roster Invitee (The Pittsburgh Pirates invited LHP Michael Plassmeyer to spring training.) |
| | LF | Non-roster Invitee (The Pittsburgh Pirates invited OF Billy McKinney to spring training.) |
| | P | Designated for Assignment (The Pittsburgh Pirates designated RHP Max Kranick for assignment.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Michael Plassmeyer to a minor league contract.) |
| | P | Signed (The Pittsburgh Pirates signed LHP Michael Plassmeyer to a minor league contract.) |
| | 3B | Signed (The Pittsburgh Pirates signed INF Francisco Acuna to a minor league contract.) |
| | SS | Signed (The Pittsburgh Pirates signed INF Sergio Alcántara to a minor league contract.) |
| | SS | Drafted Via Rule 5 (The Pittsburgh Pirates selected INF Marcos Cabrera in the Rule 5 Draft.) |
| | P | Drafted Via Rule 5 (The Pittsburgh Pirates selected RHP Fineas Del Bonta-Smith in the Rule 5 Draft.) |
| | 1B | Drafted Via Rule 5 (The Pittsburgh Pirates selected INF Seth Beer in the Rule 5 Draft.) |
| | P | Signed (The Pittsburgh Pirates signed RHP Ben Heller to a minor league contract.) |
| | P | Traded (The Atlanta Braves traded LHP Marco Gonzales to the Pittsburgh Pirates.) From |
| | P | Claimed on Unconditional Release Waivers (he Pittsburgh Pirates claimed RHP Roddery Muñoz off waivers from the Washington Nationals.) |
| | C | Signed (The Pittsburgh Pirates signed C Ali Sánchez.) |
| | P | Released (The Pittsburgh Pirates released RHP Thomas Hatch.) |
| | CF | Non-roster Invitee (The Pittsburgh Pirates invited non-roster OF Gilberto Celestino to spring training.) |
| | CF | Signed (The Pittsburgh Pirates signed OF Gilberto Celestino to a minor league contract.) |
| | CF | Signed (The Pittsburgh Pirates signed OF Gilberto Celestino to a minor league contract.) |
| | P | Released (The Pittsburgh Pirates released RHP Hunter Stratton.) |
| | P | Released (The Pittsburgh Pirates released RHP Osvaldo Bido.) |
| | P | Released (The Pittsburgh Pirates released RHP Wil Crowe.) |
| | P | Recalled From Minors Rehab (The Pittsburgh Pirates selected the contract of RHP Braxton Ashcraft from the minors.) |
| | SS | Recalled From Minors Rehab (The Pittsburgh Pirates selected the contract of INF Tsung-Che Cheng from the minors.) |
| | P | Declared Free Agency (RHP Travis MacGregor declared free agency.) |
| | P | Declared Free Agency (RHP Noe Toribio declared free agency.) |
| | P | Declared Free Agency (RHP Santiago Florez declared free agency.) |
| | P | Declared Free Agency (RHP Tahnaj Thomas declared free agency.) |
| | P | Declared Free Agency (RHP Michell Miliano declared free agency.) |
| | CF | Declared Free Agency (OF Lolo Sanchez declared free agency.) |
| | RF | Declared Free Agency (OF Cal Mitchell declared free agency.) |
| | P | Declared Free Agency (RHP Juan Minaya declared free agency.) |
| | 1B | Declared Free Agency (INF Jacob Gonzalez declared free agency.) |
| | 3B | Declared Free Agency (INF Francisco Acuna declared free agency.) |
| | SS | Declared Free Agency (INF Ryan Vilade declared free agency.) |
| | C | Declared Free Agency (C Dom Nuñez declared free agency.) |
| | P | Declared Free Agency (LHP Daniel Zamora declared free agency.) |
| | 1B | Declared Free Agency (INF Mason Martin declared free agency.) |
| | P | Declared Free Agency (LHP Braeden Ogle declared free agency.) |
| | P | Declared Free Agency (RHP Yerry De Los Santos declared free agency.) |
| | P | Declared Free Agency (RHP Oliver Garcia declared free agency.) |
| | CF | Declared Free Agency (OF Chavez Young declared free agency.) |
| | P | Declared Free Agency (RHP Wei-Chieh Huang declared free agency.) |
| | P | Declared Free Agency (RHP Beau Sulser declared free agency.) |
| | 2B | Declared Free Agency (INF Domingo Leyba declared free agency.) |
| | P | Declared Free Agency (The Pittsburgh Pirates LHP Jarlín García declared free agency.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Roansy Contreras.) |
| | P | Activated (The Pittsburgh Pirates activated LHP Jarlín García.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Thomas Hatch.) |
| | SS | Activated (The Pittsburgh Pirates activated INF Oneil Cruz.) |
| | P | Activated (The Pittsburgh Pirates activated LHP Bailey Falter from the 15-day injured list.) |
| | P | Sent to Minors (The Pittsburgh Pirates sent LHP Angel Perdomo outright to the minors.) |
| | SS | Activated (The Pittsburgh Pirates activated INF Alika Williams.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Colin Holderman.) |
| | RF | Activated (The Pittsburgh Pirates activated OF Canaan Smith-Njigba.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Luis L. Ortiz.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Max Kranick.) |
| | P | Activated (The Pittsburgh Pirates activated RHP Mike Burrows.) |
| | P | Activated (The Pittsburgh Pirates activated LHP Jackson Wolf.) |
| | P | Activated (The Pittsburgh Pirates activated RHP JT Brubaker.) |
| | RF | Declared Free Agency (Pittsburgh Pirates DH Andrew McCutchen declared free agency.) |
| | P | Declared Free Agency (Pittsburgh Pirates LHP Caleb Smith declared free agency.) |
| | LF | Sent to Minors (The Pittsburgh Pirates sent OF Miguel Andujar outright to the minors.) |
| | P | Waived (The Pittsburgh Pirates placed RHP Yerry De Los Santos on outright waivers.) |
| | P | Declared Free Agency (Pittsburgh Pirates RHP Vince Velasquez declared free agency.) |
| | P | Traded (The Pittsburgh Pirates traded RHP Cody Bolton to the Seattle Mariners.) To |
| | P | Released (The Pittsburgh Pirates released RHP Nathan Webb.) |
| | 2B | Declared Free Agency (INF Chris Owings declared free agency.) |