Nix has become the first of the six first-round quarterbacks to sign.
Former 49ers QB Alex Smith believes San Francisco's Super Bowl losses are partly due to some bad luck.
The Titans signed first-round pick JC Latham to his rookie contract, the team announced Friday.
Frank Gore Sr. played for five teams in a 16-year NFL career and now works in an advisory role with the 49ers for whom he spent most of his career.