Villa crumbled on home soil against Olympiacos.
Marseille's Europa League semi-final tie against Atalanta is finely poised going into the return after the teams drew 1-1 in Thursday's first leg in France.However, Marseille have struggled on their travels and just reaching the semi-finals was a fine achievement for a club who are outside the European places in Ligue 1 and are on their third coach of the campaign.
Bayer Leverkusen have one foot in the Europa League final after winning 2-0 at Roma on Thursday to extend their remarkable unbeaten run to 47 matches.Roma are also in a dogfight to reach next season's revamped Champions League in Serie A while Leverkusen remain on course for a Bundesliga, German Cup and Europa League treble.
Aston Villa 2-4 Olympiacos: A late missed penalty by Douglas Luiz could prove costly after Ayoub El Kaabi hit a hat-trick