Houston Astros
- 12-31,
- 5th AL West
Transactions
| Date | Player | Position | Transaction |
|---|---|---|---|
| May 18 | Jake Elmore | SS/2B | Sent to Minors by Houston |
| May 18 | José Altuve | 2B | Reinstated from Bereavement/Family Medical Emergency List by Houston |
| May 14 | Jake Elmore | SS/2B | Called Up from Minors by Houston |
| May 14 | José Altuve | 2B | Placed on Bereavement/Family Medical Emergency List by Houston |
| May 14 | Philip Humber | SP | Outrighted to Minors by Houston |
| May 12 | Édgar González | SP/RP | Signed as Free Agent by Houston (one-year contract) |
| May 12 | Philip Humber | SP | Designated for Assignment by Houston |
| May 11 | Fernando Martínez | LF/RF | Outrighted to Minors by Houston |
| May 11 | Rick Ankiel | RF/CF | Cleared Waivers and Became a Free Agent by Houston |
| May 11 | Édgar González | SP/RP | Outrighted to Minors by Houston |
| May 10 | Josh Fields | RP | Sent to Minors for Rehabilitation by Houston |
| May 9 | Rick Ankiel | RF/CF | Released by Houston |
| May 7 | Jimmy Paredes | 3B/RF/2B | Called Up from Minors by Houston |
| May 7 | Rick Ankiel | RF/CF | Designated for Assignment by Houston |
| May 7 | Fernando Martínez | LF/RF | Designated for Assignment by Houston |
| May 7 | Trevor Crowe | CF/LF/RF | Purchased From Minors by Houston |
| May 7 | J.D. Martínez | LF/RF | Recalled From Minors Rehab by Houston |
| May 6 | Brandon Laird | 3B/1B | Sent to Minors by Houston |
| May 2 | Jordan Lyles | SP | Called Up from Minors by Houston |
| May 2 | Dallas Keuchel | RP/LF/SP | Called Up from Minors by Houston |
| May 1 | Brad Peacock | SP/RP | Sent to Minors by Houston |
| May 1 | Rhiner Cruz | RP | Sent to Minors by Houston |