| | 2B | Recalled From Minors Rehab (The Chicago White Sox selected the contract of INF Zach Remillard from the minors.) |
| | RF | Traded (The Chicago White Sox traded OF Robbie Grossman to the Texas Rangers.) To |
Anthony Hoopii-Tuionetoa | | P | Traded (The Texas Rangers traded RHP Anthony Hoopii-Tuionetoa to the Chicago White Sox.) From |
| | P | Placed on 15-Day IL (The Chicago White Sox placed RHP Dominic Leone on the 15-day injured list with back tightness.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox recalled RHP Mike Clevinger from the minors.) |
| | 3B | Placed on 10-Day IL (The Chicago White Sox placed INF Danny Mendick on the 10-day injured list with a back injury.) |
| | 2B | Recalled From Minors Rehab (The Chicago White Sox recalled INF Bryan Ramos from the minors.) |
| | CF | Released (The Chicago White Sox released OF Brett Phillips.) |
| | P | Sent to Minors (The Chicago White Sox outrighted RHP Deivi García to the minors.) |
| | 2B | Sent to Minors (The Chicago White Sox sent INF Zach Remillard outright to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Prelander Berroa to the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox recalled LHP Jared Shuster from the minors.) |
| | P | Traded (The Chicago White Sox traded RP Bailey Horn to the Boston Red Sox.) To |
| | 1B | Signed (The Chicago White Sox signed free agent INF Jared Walsh to a minor league contract.) |
| | RF | Sent to Minors (The Chicago White Sox sent OF Kevin Pillar outright to the minors.) |
| | RF | Declared Free Agency (OF Kevin Pillar elected free agency.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox recalled RHP Prelander Berroa from the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Brad Keller from the minors.) |
| | P | Designated for Assignment (The Chicago White Sox designated RHP Deivi García for assignment.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Jonathan Cannon to the minors.) |
| | P | Designated for Assignment (The Chicago White Sox designated RP Bailey Horn for assignment.) |
| | CF | Recalled From Minors Rehab (The Chicago White Sox selected the contract of OF Rafael Ortega.) |
| | CF | Sent to Minors (The Chicago White Sox optioned OF Dominic Fletcher to the minors.) |
| | RF | Designated for Assignment (The Chicago White Sox designated OF Kevin Pillar for assignment.) |
| | CF | Recalled From Minors Rehab (The Chicago White Sox selected the contract of OF Tommy Pham from the minors.) |
| | 3B | Sent to Minors (The Chicago White Sox optioned INF Lenyn Sosa to the minors.) |
| | 2B | Designated for Assignment (The Chicago White Sox designated INF Zach Remillard for assignment.) |
| | 3B | Recalled From Minors Rehab (The Chicago White Sox selected the contract of INF Danny Mendick from the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Nick Nastrini to the minors.) |
| | P | Activated (The Chicago White Sox activated RHP John Brebbia from the 15-day injured list.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Josimar Cousin outright to the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox recalled LHP Jared Shuster from the minors. He will serve as the teams' 27th player in its doubleheader against the Royals.) |
| | P | Sent to Minors (The Chicago White Sox returned 27th man LHP Jared Shuster to the minors.) |
| | P | Designated for Assignment (The Chicago White Sox designated RHP Josimar Cousin for assignment.) |
| | CF | Signed (The Chicago White Sox signed OF Tommy Pham to a minor league contract.) |
| | P | Sent to Minors (The Chicago White Sox optioned SP Jared Shuster to the minors.) |
| | CF | Signed (The Chicago White Sox signed OF Tommy Pham to a minor league contract.) |
| | C | Placed on 60-Day IL (The Chicago White Sox transferred C Max Stassi on the 60-day injured list with left hip inflammation.) |
| | DH | Activated (The Chicago White Sox activated OF Eloy Jiménez from the 10-day injured list.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Justin Anderson to the minors.) |
| | 2B | Sent to Minors (The Chicago White Sox optioned INF Zach Remillard to the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Nick Nastrini from the minors.) |
| | SS | Signed (The Chicago White Sox signed INF Wilmer Difo to a minor league contract.) |
| | P | Declared Free Agency (The Chicago White Sox released RHP Bryan Shaw.) |
| | SS | Signed (The Chicago White Sox signed INF Wilmer Difo to a minor league contract.) |
| | P | Signed (The Chicago White Sox signed RHP Cory Abbott to a minor league contract.) |
| | P | Designated for Assignment (The Chicago White Sox designated RP Bryan Shaw for assignment.) |
| | RF | Sent to Minors (The Chicago White Sox optioned OF Oscar Colás to the minors.) |
| | 2B | Recalled From Minors Rehab (The Chicago White Sox recalled INF Zach Remillard from the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RP Justin Anderson from the minors.) |
| | 3B | Placed on 60-Day IL (The Chicago White Sox transferred INF Yoan Moncada from the 15-day injured list to the 60-day injured list.) |
| | RF | Recalled From Minors Rehab (The Chicago White Sox recalled OF Oscar Colás from the minors.) |
| | 3B | Placed on 15-Day IL (The Chicago White Sox placed INF Yoán Moncada on the 15-day injured list.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox recalled LHP Jared Shuster from the minors.) |
| | P | Placed on 15-Day IL (The Chicago White Sox placed RHP John Brebbia on the 15-day injured list.) |
| | 3B | Recalled From Minors Rehab (The Chicago White Sox recalled INF Lenyn Sosa from the minors.) |
| | P | Traded (The Chicago White Sox traded RHP Alex Speas to the Oakland Athletics.) To |
| | CF | Placed on 10-Day IL (The Chicago White Sox placed OF Luis Robert on the 10-day injured list.) |
| | P | Designated for Assignment (The Chicago White Sox sent RHP Alex Speas to the minors.) |
| | SS | Traded (The Chicago White Sox traded SS Jose Rodriguez to the Philadelphia Phillies.) To |
| | DH | Placed on 10-Day IL (The Chicago White Sox placed OF Eloy Jiménez on the 10-day injured list.) |
| | RF | Recalled From Minors Rehab (The Chicago White Sox selected OF Robbie Grossman from the minors.) |
| | SS | Designated for Assignment (The Chicago White Sox designated INF Josè Rodriguez for assignment.) |
| | P | Signed (The Chicago White Sox signed RHP Mike Clevinger.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Mike Clevinger to the minors.) |
| | C | Sent to Minors (The Chicago White Sox sent C Max Stassi to the minors on a rehab assignment.) |
| | P | Signed (The Chicago White Sox signed RHP Mike Clevinger.) |
| | P | Traded (The Chicago White Sox traded RHP Jake Cousins to the New York Yankees.) To |
| | | Signed (The Chicago White Sox signed LHP Tommy Vail to a minor league contract.) |
| | | Signed (The Chicago White Sox signed LHP Tommy Vail to a minor league contract.) |
| | RF | Sent to Minors (The Chicago White Sox sent OF Robbie Grossman to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Drew Thorpe to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Brad Keller to the minors.) |
| | P | Designated for Assignment (The Chicago White Sox designated LHP Sammy Peralta for assignment.) |
| | P | Placed on 15-Day IL (The Chicago White Sox placed RHP Jimmy Lambert on the 15-day injured list.) |
| | P | Placed on 60-Day IL (The Chicago White Sox placed LHP Shane Drohan on the 60-day injured list.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Jordan Leasure from the minors.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Bryan Shaw.) |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Dominic Leone.) |
| | P | Placed on 60-Day IL (The Chicago White Sox placed RHP Jimmy Lambert on the 60-day injured list.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Touki Toussaint outright to the minors.) |
| | P | Drafted (The Chicago White Sox designated RHP Touki Toussaint for assignment.) |
| | C | Recalled From Minors Rehab (The Chicago White Sox recalled C Korey Lee from the minors.) |
| | C | Placed on 10-Day IL (The Chicago White Sox placed C Max Stassi on the 10-day injured list.) |
| | RF | Signed (The Chicago White Sox signed OF Kevin Pillar.) |
| | P | Declared Free Agency (RHP Jesse Chavez elected free agency.) |
| | RF | Non-roster Invitee (The Chicago White Sox signed OF Robbie Grossman to a minor league contract with an invitation to spring training.) |
| | RF | Signed (The Chicago White Sox signed LF Kevin Pillar.) |
| | RF | Released (The Chicago White Sox released OF Kevin Pillar.) |
| | 1B | Released (The Chicago White Sox released INF Mike Moustakas.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Prelander Berroa to the minors.) |
| | C | Sent to Minors (The Chicago White Sox optioned C Korey Lee to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Jonathan Cannon to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned LHP Jared Shuster to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Nicholas Padilla to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned LHP Bailey Horn to the minors.) |
| | 3B | Sent to Minors (The Chicago White Sox optioned INF Lenyn Sosa to the minors.) |
| | CF | Designated for Assignment (The Chicago White Sox designated OF Peyton Burdick for assignment.) |
| | CF | Traded (The San Diego Padres traded OF Samuel Zavala to the Chicago White Sox.) From |
| | P | Traded (The Chicago White Sox traded RHP Dylan Cease to the San Diego Padres.) To |
| | P | Traded (The San Diego Padres traded RHP Steven Wilson to the Chicago White Sox.) From |
| | P | Traded (The San Diego Padres traded RHP Drew Thorpe to the Chicago White Sox.) From |
| | P | Traded (The San Diego Padres traded RHP Jairo Iriarte to the Chicago White Sox.) From |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Alex Speas to the minors.) |
| | 1B | Sent to Minors (The Chicago White Sox sent INF Tim Elko to the minors.) |
| | CF | Sent to Minors (The Chicago White Sox optioned OF Zach DeLoach to the minors.) |
| | SS | Sent to Minors (The Chicago White Sox sent INF Colson Montgomery to the minors.) |
| | CF | Sent to Minors (The Chicago White Sox optioned OF Peyton Burdick to the minors.) |
| | C | Sent to Minors (The Chicago White Sox sent C Carlos Pérez to the minors.) |
| | 2B | Sent to Minors (The Chicago White Sox optioned INF Bryan Ramos to the minors.) |
| | RF | Sent to Minors (The Chicago White Sox optioned OF Oscar Colás to the minors.) |
| | P | Signed (The Chicago White Sox signed RHP Brad Keller to a minor league contract with an invitation to major-league camp.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Josimar Cousin to the minors.) |
| | C | Sent to Minors (The Chicago White Sox sent C Adam Hackenberg to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned RHP Davis Martin to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Ky Bush to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Edgar Navarro to the minors.) |
| | C | Sent to Minors (The Chicago White Sox sent C Edgar Quero to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned LHP Sammy Peralta to the minors.) |
| | SS | Sent to Minors (The Chicago White Sox optioned INF Josè Rodriguez to the minors.) |
| | P | Signed (The Chicago White Sox signed RHP Brad Keller to a minor league contract with an invitation to major-league camp.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Lane Ramsey to the minors.) |
| | P | Sent to Minors (The Chicago White Sox sent LHP Fraser Ellard to the minors.) |
| | P | Sent to Minors (The Chicago White Sox optioned LHP Jake Eder to the minors.) |
| | P | Traded (The Chicago White Sox traded RHP Matthew Thompson to the Chicago Cubs.) To |
| | P | Traded (The Chicago Cubs traded LHP Bailey Horn to the Chicago White Sox.) From |
| | P | Placed on 60-Day IL (The Chicago White Sox placed RHP Jesse Scholtens on the 60-day injured list.) |
| | CF | Claimed on Unconditional Release Waivers (The Chicago White Sox claimed OF Peyton Burdick off waivers.) |
| | P | Placed on 60-Day IL (The Chicago White Sox placed RHP Matt Foster on the 60-day injured list.) |
| | SS | Signed (The Chicago White Sox signed INF Lucius Fox to a minor league contract.) |
| | 1B | Non-roster Invitee (The Chicago White Sox signed INF Mike Moustakas to a minor league contract with an invitation to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox signed RHP Jesse Chavez to a minor league contract with an invitation to spring training.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Lane Ramsey outiright to the minors.) |
| | P | Designated for Assignment (The Chicago White Sox designated RHP Lane Ramsey for assignment.) |
| | P | Traded (The Chicago White Sox traded RHP Cristian Mena to the Arizona Diamondbacks.) To |
| | CF | Traded (The Arizona Diamondbacks traded OF Dominic Fletcher to the Chicago White Sox.) From |
| | P | Traded (The Seattle Mariners traded RHP Prelander Berroa to the Chicago White Sox.) From |
| | CF | Traded (The Seattle Mariners traded OF Zach DeLoach to the Chicago White Sox.) From |
| | P | Traded (The Chicago White Sox traded RHP Gregory Santos to the Seattle Mariners.) To |
| | RF | Signed (The Chicago White Sox signed OF Kevin Pillar to a minor league contract.) |
| | RF | Signed (The Chicago White Sox signed OF Kevin Pillar to a minor league contract.) |
| | P | Signed (The Chicago White Sox signed RHP Aaron McGarity to a minor league contract.) |
| | SS | Waived (The Chicago White Sox waived INF Romy González.) |
| | SS | Designated for Assignment (The Chicago White Sox designated INF Romy González for assignment.) |
| | P | Signed (The Chicago White Sox signed RHP John Brebbia.) |
| | P | Signed (The Chicago White Sox signed RHP Joe Barlow to a minor league contract.) |
| | CF | Signed (The Chicago White Sox signed OF Rafael Ortega to a minor league contract.) |
| | CF | Signed (The Chicago White Sox signed OF Rafael Ortega to a minor league contract.) |
| | P | Non-roster Invitee (The Chicago White Sox signed RHP Jake Woodford to a minor league contract with an invitation to spring training.) |
| | 2B | Sent to Minors (The Chicago White Sox outrighted INF Zach Remillard to the minors.) |
| | P | Signed (The Chicago White Sox signed RHP Chad Kuhl to a minor league contract.) |
| | 2B | Designated for Assignment (The Chicago White Sox designated INF Zach Remillard for assignment.) |
| | C | Sent to Minors (The Chicago White Sox sent C Carlos Pérez outright to the minors.) |
| | C | Designated for Assignment (The Chicago White Sox designated C Carlos Pérez for assignment.) |
| | P | Signed (The Chicago White Sox signed RHP Chris Flexen.) |
| | P | Designated for Assignment (The Chicago White Sox designated RHP Declan Cronin for assignment.) |
| | P | Signed (The Chicago White Sox signed LHP Tim Hill.) |
| | RF | Declared Free Agency (OF Adam Haseley declared free agency.) |
| | C | Traded (The Atlanta Braves traded C Max Stassi to the Chicago White Sox.) From |
| | P | Sent to Minors (The Chicago White Sox outrighted RHP Edgar Navarro to the minors.) |
| | P | Non-roster Invitee (The Chicago White Sox invited non-roster RHP Jake Cousins to spring training.) |
| | P | Drafted Via Rule 5 (The Chicago White Sox selected LHP Shane Drohan in the Rule 5 Draft.) |
| | P | Signed (The Chicago White Sox signed RHP Jake Cousins to a minor league contract.) |
| | P | Signed (The Chicago White Sox signed RHP Jake Cousins to a minor league contract.) |
| | P | Signed (The Chicago White Sox signed RHP Erick Fedde.) |
| | RF | Sent to Minors (The Chicago White Sox assigned OF Adam Haseley outright to the minors.) |
| | CF | Signed (The Chicago White Sox signed OF Wynton Bernard to a minor league contract.) |
| | RF | Declared Free Agency (OF Adam Haseley declared free agency.) |
| | P | Sent to Minors (The Chicago White Sox sent RHP Nicholas Padilla outright to the minors.) |
| | CF | Signed (The Chicago White Sox signed OF Wynton Bernard to a minor league contract.) |
| | RF | Designated for Assignment (The Chicago White Sox designated OF Adam Haseley for assignment.) |
| | RF | Non-roster Invitee (The Chicago White Sox signed OF Mark Payton to a minor league contract with an invitation to spring training.) |
| | P | Signed (The Chicago White Sox signed RHP Justin Anderson to a minor league contract.) |
| | SS | Signed (The Chicago White Sox signed INF Paul DeJong.) |
| | SS | Traded (The Atlanta Braves traded INF Braden Shewmake to the Chicago White Sox.) From |
| | P | Traded (The Chicago White Sox traded LHP Aaron Bummer to the Atlanta Braves.) To |
| | P | Traded (The Atlanta Braves traded RHP Riley Gowens to the Chicago White Sox.) From |
| | 2B | Traded (The Atlanta Braves traded INF Nicky Lopez to the Chicago White Sox.) From |
| | P | Traded (The Atlanta Braves traded RHP Michael Soroka to the Chicago White Sox.) From |
| | P | Traded (The Atlanta Braves traded LHP Jared Shuster to the Chicago White Sox.) From |
| | P | Recalled From Minors Rehab (The Chicago White Sox selected the contract of RHP Cristian Mena from the minors.) |
| | P | Activated (The Chicago White Sox selected the contract of LHP Jake Eder from the minors.) |
| | P | Declared Free Agency (LHP Nate Fisher elected free agency.) |
| | C | Declared Free Agency (C Sebastián Rivero elected free agency.) |
| | SS | Declared Free Agency (INF Laz Rivera elected free agency.) |
| | CF | Declared Free Agency (OF Trayce Thompson elected free agency.) |
| | P | Declared Free Agency (RHP Alejandro Mateo elected free agency.) |
| | LF | Declared Free Agency (OF Anderson Comas elected free agency.) |
| | P | Declared Free Agency (RHP Chris Muller elected free agency.) |
| | RF | Declared Free Agency (OF Victor Reyes elected free agency.) |
| | C | Declared Free Agency (C Xavier Fernández elected free agency.) |
| | P | Declared Free Agency (RHP Nick Gallagher elected free agency.) |
| | P | Declared Free Agency (LHP Garrett Davila elected free agency.) |
| | P | Declared Free Agency (LHP Austin Warner elected free agency.) |
| | P | Declared Free Agency (RHP J.B. Olson elected free agency.) |
| | P | Declared Free Agency (RHP Luke Farrell elected free agency.) |
| | RF | Declared Free Agency (OF Luis Mieses elected free agency.) |
| | LF | Declared Free Agency (OF Clint Frazier elected free agency.) |
| | SS | Declared Free Agency (INF Moisés Castillo declared free agency.) |
| | 2B | Declared Free Agency (INF Nate Mondou declared free agency.) |
| | SS | Declared Free Agency (INF Erik González declared free agency.) |
| | SS | Activated (The Chicago White Sox activated INF Romy González.) |
| | P | Activated (The Chicago White Sox activated RHP Jimmy Lambert.) |
| | P | Activated (The Chicago White Sox activated RHP Matt Foster.) |
| | SS | Declared Free Agency (INF Tim Anderson elected free agency.) |
| | P | Activated (The Chicago White Sox activated RHP Gregory Santos.) |
| | CF | Activated (The Chicago White Sox activated OF Luis Robert.) |
| | P | Activated (The Chicago White Sox activated RHP Edgar Navarro.) |
| | CF | Sent to Minors (The Chicago White Sox outrighted OF Trayce Thompson to the minors.) |
| | P | Activated (The Chicago White Sox activated RHP Michael Kopech.) |
| | P | Declared Free Agency (The Chicago White Sox RHP Liam Hendriks declared free agency.) |
| | P | Activated (The Chicago White Sox activated RHP Davis Martin.) |
| | RF | Activated (The Chicago White Sox activated RF Adam Haseley.) |
| | P | Activated (The Chicago White Sox activated RHP Alex Speas.) |
| | P | Activated (The Chicago White Sox activated RHP Jesse Scholtens.) |
| | P | Declared Free Agency (Chicago White Sox RHP Mike Clevinger declared free agency.) |
| | LF | Sent to Minors (The Chicago White Sox outrighted OF Clint Frazier to the minors.) |
| | P | Activated (The Chicago White Sox activated RHP Nicholas Padilla.) |
| | 2B | Activated (The Chicago White Sox activated INF Bryan Ramos.) |
| | LF | Activated (The Chicago White Sox activated LF Clint Frazier.) |
| | SS | Activated (The Chicago White Sox activated SS Josè Rodriguez.) |
| | RF | Activated (The Chicago White Sox activated RF Oscar Colas.) |
| | SS | Declared Free Agency (Chicago White Sox INF Elvis Andrus declared free agency.) |
| | P | Declared Free Agency (Chicago White Sox RHP José Ureña declared free agency.) |
| | C | Declared Free Agency (Chicago White Sox C Yasmani Grandal declared free agency.) |
| | P | Declared Free Agency (Chicago White Sox RHP Bryan Shaw declared free agency.) |