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Saquon Barkley returns triumphant for the Giants' home opener, Dalvin Cook hunts for touchdowns in Philadelphia, and Nick Chubb greets a plus matchup in the Jets.
At quarterback, Jalen Hurts looks to get a hot streak going against the Vikings, Kyler Murray searches for answers after a dismal Week 1, and Tom Brady confronts his Tampa nemesis New Orleans.
In the receiver ranks, Deebo Samuel prays for better weather against the Seahawks and Gabe Davis hopes to keep his hype train rolling on Monday Night Football.
Up the seam, Dallas Goedert settles into a plus scoring environment vs. the Vikings and Dawson Knox fights for scores against Tennessee.
Week 2 Rankings: Quarterback | Running Back | Wide Receiver | Tight End/Kickers/Defense