Guinness Six Nations: England v Wales
Venue: Twickenham Stadium Date: Saturday, 10 February Kick-off: 16:45 GMT
Coverage: Listen on BBC Radio 5 Live, live text on BBC Sport website and app, watch on ITV1
England captain Jamie George expects to be "very emotional" when he leads out the team for the first time in a Six Nations match at Twickenham.
George's reign as skipper began with victory in Rome, but he says walking out at a sold-out home of English rugby to face Wales will be "special".
"It's huge. It's a dream come true," George told BBC Radio 5 Live.
"Being at Twickenham, singing the anthem and that walkout will be a very emotional moment for me."
George, who will win his 87th cap on Saturday, added: "I never thought I would be in this position."
England were beaten in a World Cup warm-up game by Fiji in their last match at Twickenham, five months after slumping to their record home defeat against France in the Six Nations.
England are unchanged from their opening win over Italy and George, 33, says the players are excited about the visit of rivals Wales.
"I think it's special it's against Wales. The first thing you think of is the history of the fixture," said George.
"Our recent record at Twickenham has been poor and we have been very outspoken about how we want Twickenham to be great again, so we have the responsibility to do that and what a privilege that is.
"Usually on Monday we have a tactical meeting about the rugby stuff but [head coach] Steve [Borthwick] parked that for a bit this week to talk about the opportunity we have to be back at home against Wales and we touched on the emotion.
"Then the senior players took over, which was great.
"We have extended the walk [to the stadium] from the bus and there have been changes in the changing room, which will hopefully make a difference to the team."