WASHINGTON (AP) -- Pat Valaika, Pedro Severino and Anthony Santander homered during a five-run rally in the eighth inning as the Baltimore Orioles roughed up Washington's relievers and beat the Nationals 5-3 Saturday night.
Nationals starter Austin Voth pitched five sharp innings, and the Orioles went into eighth with just two hits and trailing 3-0.
Sean Doolittle relieved and Baltimore, which routed the World Series champions 11-0 on Friday night, began the eighth with back-to-back, pinch-hit homers by Valaika and Severino.
Daniel Hudson (1-1) took over with one out and after a walk and single, Santander hit his third homer of the season into the left-field bleachers.
''That was a good start to the eighth inning, back-to-back homers,'' Santander said.
Doolittle, who led Washington with 29 saves last season, has a 18.00 ERA this season in four appearances out of the Nationals bullpen.
''I don't have a ton of answers myself right now, so I'll do my best with questions,'' Doolitte said before talking to the media.
''I should be able to get through an inning and it just hasn't come together. I feel terrible. I'm letting the team down. I want to help. I want to be a part of that group,'' he said.
Manager Dave Martinez stuck behind Doolittle, telling reporters: ''I'm not going to give up on him. We've got to figure this out.''
Juan Soto hit his first home run of the season in the second to give Washington a 1-0 lead. Eric Thames had an RBI double in the sixth as the Nationals went up 3-0.
Soto, who started the season on the COVID-19 injured list, also singled in the fourth inning for his second multihit effort in three games since returning to the lineup.
It was the 21-year old's first homer since Game 6 of the 2019 World Series. Soto had five home runs last postseason.
Shawn Armstrong (1-0) allowed just one hit and struck out two in 1 1/2 innings of middle relief.
Miguel Castro earned his first save of the season with a scoreless ninth.
WELCOME TO THE BIGS
The Orioles recalled left-hander Keegan Akin from their alternate training site and optioned outfielder Cedric Mullins to the same facility.
Akin was Baltimore's second-round in the 2016 draft and is on the brink of playing in his first big league game after going 6-7 for Triple-A Norfolk last season.
''We're excited for him to potentially make his debut,'' manager Brandon Hyde said, noting that Akin will be the long man in the bullpen for the remainder of the series.
Orioles: Right-handed reliever Hunter Harvey (right forearm strain) is still around three weeks away from making his season debut. ''We're very encouraged about his progress, and I'm hopeful we'll get him at some point at the end of this month,'' manager Brandon Hyde said. ... Severino was hit by a pitch in the left hand in the ninth. He shook it off and stole second.
Nationals: RHP Max Scherzer (right hamstring) was scheduled to throw a bullpen session for the second day in a row on Saturday. Martinez said if all goes well it would set up for Scherzer to start Tuesday at the New York Mets. ''My biggest concern is Scherzer being able to push off his leg,'' Martinez said. ''If he can do that, I think he's going to be alright.''
Orioles: Asher Wojciechowski (0-2, 5.40 ERA) will start Sunday in the series finale on three days rest. He threw only 67 pitches in his last outing Wednesday against Miami, allowing two runs in five innings.
Nationals: World Series MVP Stephen Strasburg will make his season debut on Sunday. The 32-year old had missed his first two starts of the season because of a nerve issue in his right hand.
More AP baseball: https://apnews.com/MLB and https://twitter.com/AP-Sports