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The Paralysis Pill From ‘Run’ Is Based on a Real Drug—& Here Are Its Dangerous Side Effects

If you’ve watched Run on Hulu, you may have the same question as us: What is Trigoxin and is it a real drug? Since its premiere on November 20, Run has become Hulu’s most watched original film.

The movie stars Sarah Paulson as Diane, the mother of a teenage daughter named Chloe, who is chronically ill with arrhythmia, hemochromatosis, diabetes and paralysis. Due to her illnesses, Chloe uses a wheelchair and takes a cocktail of pills her mom gives to her each day. However, Chloe isn’t really sick. As viewers learn, Diane has been giving Chloe a mysterious green pill since she was a child. When Chloe asks her mom what the pill is, Diane...

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