| | RB | Signed/unrest FA (One-year contract (through 2018)) From |
| | LB | Signed/draft choice (Four-year contract (through 2021)) |
| | S | Signed/draft choice (Four-year contract (through 2021)) |
| | CB | Signed/draft choice (Four-year contract (through 2021)) |
| | DT | Signed/draft choice (Four-year contract (through 2021)) |
| | LB | Signed (Four-year contract (through 2021)) |
| | DE | Signed/draft choice (Four-year contract (through 2021)) |
| | TE | Signed/draft choice (Four-year contract (through 2021)) |
| | RB | Acquired from waiver (Signed) From |
| | RB | Signed (One-year contract (through 2018)) From |
| | S | Signed (One-day contract) To |
| | TE | Cut (Signed) |
| | T | Signed (Signed) From |
| | G | Signed (Signed) |
| | G | Signed (Signed) |
| | G | Signed (Signed) |
| | LB | Signed (Signed) |
| | QB | Signed (Signed) |
| | RB | Signed (Signed) |
| | DT | Signed (Signed) |
| | TE | Re-signed (Two-year extension (through 2020)) |
| | LB | Team exercises option (Fifth-year option on rookie contract) |
| | TE | Suspended (4 games (NFL Policy on PEDs)) |
| | QB | Acquired from waiver (Signed) From |
| | TE | Signed (One-year contract (through 2018)) To |
| | WR | Signed/unrest FA (One-year contract (through 2018)) To |
| | LB | Suspended (4 games (NFL Policy on PEDs)) |
| | TE | Signed (Two-year contract (through 2019)) To |
| | WR | Signed/unrest FA (One-year contract (through 2018)) To |
| | T | Re-signed/unrest FA (One-year contract (through 2018)) |
| | CB | Re-signed/unrest FA (One-year contract (through 2018)) |
| | S | Signed (Two-year contract (through 2019)) From |
| | CB | Signed/unrest FA (Two-year contract (through 2019)) From |
| | T | Signed/unrest FA (One-year contract (through 2018)) From |
| | WR | Signed (Three-year contract (through 2020)) From |
| | T | Acquired from waiver (Signed) From |
| | TE | Signed/unrest FA (Three-year contract (through 2020)) To |
| | G | Signed/unrest FA (Five-year contract (through 2022)) To |
| | DT | Signed/unrest FA (Three-year contract (through 2020)) From |
| | G | Declared Free Agent (Signed) |
| | TE | Declared Free Agent (Signed) |
| | CB | Declared Free Agent (Signed) |
| | T | Declared Free Agent (Signed) |
| | QB | Declared Free Agent (Signed) |
| | WR | Traded (for CB Daryl Worley) From |
| | WR | Declared Free Agent (Signed) |
| | TE | Declared Free Agent (Signed) |
| | DT | Signed/unrest FA (Five-year contract (through 2022) To |
| | CB | Signed (One-year contract (through 2018)) To |
| | WR | Declared Free Agent (Signed) |
| | G | Declared Free Agent (Signed) |
| | S | Declared Free Agent (Signed) |
| | DT | Declared Free Agent (Signed) |
| | LB | Declared Free Agent (Signed) |
| | DE | Re-signed (One-year contract (through 2018)) |
| | WR | Declared Free Agent (Signed) |
| | T | Declared Free Agent (Signed) |
| | CB | Traded (for WR Torrey Smith) To |
| | RB | Signed (Two-year contract (through 2019)) To |
| | DT | Re-signed/excl. FA (One-year tender (through 2018)) |
| | TE | Re-signed/excl. FA (One-year tender (through 2018)) |
| | C | Re-signed/excl. FA (One-year tender (through 2018)) |
| | WR | Re-signed/excl. FA (One-year tender (through 2018)) |
| | P | Re-signed/excl. FA (One-year tender (through 2018)) |
| | CB | Cut (Signed) |
| | K | Re-signed (Four-year contract (through 2021)) |
| | S | Signed (Three-year contract (through 2020)) To |
| | RB | Cut (Signed) |
| | T | Acquired from waiver (Signed) To |
| | T | Cut (Signed) |
| | S | Cut (Signed) |
| | DE | Cut (Signed) |