DENVER -- Devin Setoguchi had two goals and an assist, Niklas Backstrom stopped 28 shots and the Minnesota Wild beat the Colorado Avalanche 6-4 on Saturday.
Ryan Suter and Pierre-March Bouchard had a goal and assist each for the Wild, who swept the home-and-home with Colorado.
Cal Clutterbuck and Kyle Brodziak also had goals for Minnesota (15-10-2).
Setoguchi's big game included a career-best plus-4, which helped Backstrom improve to 23-5-3 all-time against Colorado.
Gabriel Landeskog had a goal and an assist and P.A. Parenteau, Chuck Kobasew and John Mitchell also scored for the Avalanche, who have dropped three straight.
Goaltender Jean-Sebastien Giguere got his first home start but it wasn't a pleasant one for the veteran. He allowed three goals on 10 shots in the first 9:04. He didn't get much help from his skaters, who were still searching for the loose puck on two of the Wild goals.
Suter and Setoguchi scored 1:44 apart early in the first and Clutterbuck made it 3-0 midway through when he shot one through the legs of Giguere from a bad angle.
Mitchell scored with at 14:11 of the first to make it 3-1, but Brodziak answered three minutes later.
Semyon Varlamov replaced Giguere to start the second, and it sparked the Avalanche (10-13-4). Parenteau and Landeskog scored to cut the lead to one before Bouchard's unassisted goal at 12:02 made it 5-3.
Setoguchi's goal midway through the third made it a three-goal game before Kobasew scored with 1:53 left. Varlamov was pulled for an extra skater but Colorado couldn't get any closer.
Notes: Avalanche forward Milan Hejduk was a healthy scratch. Hejduk missed five games with a torso injury but played in Minnesota on Thursday. ... Wild forward Jason Zucker missed his second game in a row with an upper body injury. Zucker suffered the injury Tuesday when he was checked by Anaheim's Corey Perry. Perry received a four-game suspension for the hit. ... Colorado defenseman Ryan Wilson was out after aggravating his injured ankle. He suffered the injury Feb. 2 against the Edmonton Oilers and missed 15 games before returning Sunday against the San Jose Sharks. ... Minnesota defenseman Brett Clark, signed earlier this week, was a healthy scratch for the second straight game. ... The NHL changed the scoring on a Colorado goal from Thursday. Originally, Parenteau was credited with the Avalanche's third goal in the 5-3 loss to Minnesota but it was changed to Matt Duchene, his 12th.