Detroit Lions (1-0) at Arizona Cardinals (0-1)
Sunday, 4:05 p.m. ET, at University of Phoenix Stadium, Glendale, Ariz. - TV: FOX
*TV announcers: Sam Rosen, Heath Evans, Molly McGrath
*Keys to the game: The Cardinals haven't entirely addressed the ills of their offensive line but could catch a break if DT Nick Fairley (shoulder) can't play. With time to get to his launch point, QB Carson Palmer has two superior receivers in Larry Fitzgerald and Michael Floyd. Palmer was hurried on more than half of his pass attempts last week. Coach Bruce Arians will vary blocking schemes but also use empty sets and shotgun to set Palmer up to attack the Lions' average secondary. The Lions put up 469 yards last week, including 191 from RB Reggie Bush. The Vikings bracketed WR Calvin Johnson with a cornerback and safety on every snap, leaving Bush and slot receiver Nate Burleson (six catches, 78 yards) open on short and intermediate routes. Johnson had 10 catches for 121 yards in last year's loss to Arizona and will again draw CB Patrick Peterson is man-help coverage. QB Matt Stafford is turnover-conscious, which leads him to the 6-5 Johnson and 6-5 TE Brandon Pettigrew when plays break down. Stafford threw three interceptions against the Cardinals last season.
*Matchup to watch - Lions DE Ezekiel Ansah vs. Cardinals LT Levi Brown - Brown was a weak spot last week against the Rams, yielding three sacks and a holding call. Ansah, a rookie, is not polished but his athleticism presents challenges for Brown.
*Player spotlight - Cardinals G Paul Fanaika: In only his second career start, Fanaika steps into the pressure-cooker. With help needed on the edges, the Cardinals cannot afford to be weak up the middle.
*Fast facts: Since 2007, Fitzgerald leads the NFL with 64 touchdown catches. ... Since 2008, Johnson leads the NFL with 50 TD receptions.
WHO WILL WIN AND WHY
He who has the ball last ... it could come down to a pair of placekickers, and Cardinals PK Jay Feely needs it most having found his way into Arians' doghouse with poor play last week.
*Our pick: Cardinals 29-26