The Chilli Boys had a great 2015/16 campaign as they finished sixth in the league and they qualified for this season's MTN8 Cup. They recorded nine wins and three defeats at home.
Marc Van Heerden, Linda Shiba and Simphiwe Mtsweni were all signed by the Chilli Boys. But Menzi Masuku, who joined the club from Orlando Pirates, was their marquee signing.
Former Bafana Bafana international Thamsanqa Sangweni has been appointed new Chippa captain and he will be hoping to lead the team to victory against Stars.
Meanwhile, Stars will be eyeing Chippa's scalp when the two teams lock horns in their league opener.
Ea Lla Koto had a poor 2015/16 campaign which saw them finish 12th on the league table. They registered four wins and nine defeats on the road.
The club strengthened their squad during the Transfer Window bringing in David Booysen, Joseph Okomu and Sinethemba Jantjie.
Stars midfielder Makhehleni Makhaula is set to miss the clash against Chippa due to an injury. However, Angelo Kerspuy is back from injury and he might feature against the Chilli Boys.
In Polokwane, Baroka FC will be making their Absa Premiership debut when they host Ajax Cape Town at the Old Peter Mokaba Stadium on Tuesday.
Bakgaga secured their place in the top flight league after winning the 2015/16 National First Division (NFD) title. They recorded nine wins and one defeat at home.
Geofrey Massa, Jacky Motshegwa (Loan deal extended) and James Bell were the three players with Absa Premiership experience signed by the club during the Transfer Window.
Baroka captain Olaleng Shaku remains a key player for the team. The midfielder will be hoping to lead the team to victory over Ajax.
Meanwhile, Ajax will be targeting nothing but a win over Baroka when two teams face each other in their league opener.
The Urban Warriors missed out on the 2016 MTN8 Cup after finishing tenth on the Absa Premiership standings. They registered four wins and nine defeats on the road.
During the off-season, the club signed Joaquim Lupeta, Thabo Mosadi, Roscoe Pietersen as well as Neo Makua from Bidvest Wits academy.
With Prince Nxumalo out injured, Portuguese striker Lupeta is expected to lead Ajax's attack in Polokwane.
Ajax's new city rivals Cape Town City FC will make their Absa Premiership debut against Polokwane City at the Cape Town Stadium on Tuesday.
City, who were previously known as Mpumalanga Black Aces, finished fourth on the Absa Premiership table and they qualified for this season's MTN8 Cup.
The new Mother City side have been one of the busiest clubs in the Transfer Window. Lehlohonolo Majoro, James Brown and Tshepo Gumede headline their new signings.
Lebogang Manyama has been appointed City captain and the attacking midfielder will be out to inspire his side to victory in Cape Town.
Meanwhile, Polokwane will be hoping to avoid a defeat in their first Absa Premiership match of the 2016/17 campaign when they face Cape Town.
Rise and Shine survived relegation from the elite league last season as they finished 13th. They won once and lost eight times on the road.
The club brought in experienced PSL players like Thabiso Semenya, Rodney Ramagalela and Walter Maponyane during the Transfer Window.
Polokwane retained Thobani Mncwango's services despite interest from Orlando Pirates and the striker will be looking to fire his side past Cape Town in the Mother City.