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Texas defensive end Jackson Jeffcoat is out for the season with a right pectoral muscle rupture that he sustained against Oklahoma on Saturday, ESPN.com reported Monday.
The junior will have surgery to repair the damage, according to Texas trainer Kenny Boyd.
Cedric Reed and Reggie Wilson will most likely fill in for Jeffcoat, with Wilson considered the more productive of the two.
Quarterback David Ash sustained a left wrist injury in the 63-21 loss. An X-ray did not show a fracture and he has not been ruled out for the Longhorns' next game against Baylor.
Also, defensive tackle Brandon Moore (neck sprain) and junior tackle Donald Hawkins (ankle) will be evaluated during the week before a decision is made on their status.
Jeffcoat has been projected as an early-round NFL draft pick if he elects to come out. He has 11 tackles for loss, four sacks, six quarterback hurries, two forced fumbles and a fumble recovery for a touchdown.
Jeffcoat missed all of spring practice because he had surgery to repair his left pectoral muscle after last season.
Junior Case McCoy would likely take over at quarterback if Ash is ruled out. McCoy was 5 for 8 for 102 yards with two touchdowns against Oklahoma.
Ash was 13 of 29 for 113 yards with two interceptions against the Sooners.