TORONTO -- Guard Manu Ginobili came off the bench to score 16 points while adding nine assists as the San Antonio Spurs defeated the Toronto Raptors 116-103 on Tuesday.

Guard Tony Parker added 15 points for the Spurs with guard Danny Green and forwards Tim Duncan and Aron Baynes chipping in 14 each. Guard Marco Belinelli had 12 and guard Patty Mills had 11 for the Spurs.

Forward Amir Johnson and guard DeMar DeRozan led the Raptors with 19 points each with Johnson adding nine rebounds. Center Jonas Valanciunas and guard-forward Terrence Ross scored 14 each and guard Kyle Lowry scored 11 points with seven assists and seven rebounds. Guard Dwight Buycks added 10 from the bench.

The Spurs (16-4) won their past six games against the Raptors (7-13), who last beat them Jan. 3, 2010, at the Air Canada Centre.

Ross, usually a guard, started at small forward for the Raptors instead of forward Landry Fields and made four 3-pointers.

The Spurs took control of the game in the third quarter and Mills scored three 3-pointers to open the fourth quarter to take a 102-82 lead.

Duncan scored nine points in the third quarter as the Spurs stretched a six-point half-time lead to 15 points going into the fourth quarter. A 3-point jump shot by Lowry with 3:22 left in the third quarter cut San Antonio's lead to seven but the Spurs took command of the game from the Raptors who were undermanned because four players acquired in a trade with Sacramento had not yet arrived.

The Spurs entered the second quarter trailing by 12, but led 43-40 with 6:50 to play in the half after Baynes scored six consecutive points.

The Raptors, who led by as many as 14 in the first quarter, regained a three-point lead in the second quarter but with Parker scoring six of San Antonio's final eight points of the half. The Spurs led 59-53 after going 12 for 19 from the field in the second quarter.

The Raptors led 36-24 after the first quarter led by Johnson and Valanciunas, who scored 10 points each.

NOTES: Spurs C Tiago Splitter, who first experienced discomfort in his left calf during the second half of a Dec. 2 win over the Atlanta Hawks, did not make the trip to Toronto. ... The Raptors waived G D.J. Augustin on Monday after officially announcing the trade of F Rudy Gay, F Quincy Acy and C Aaron Gray to the Sacramento Kings for G Greivis Vasquez, F John Salmons, F Chuck Hayes and F Patrick Patterson. None of the new players was in uniform Tuesday. ... Raptors F Tyler Hansbrough (sprained left shoulder) did not play Tuesday but could be ready to play against the Philadelphia 76ers on Friday. ... The Spurs began a stretch of four games in five days Tuesday. They play the Bucks in Milwaukee on Wednesday.