Jacksonville Jaguars quarterback Blaine Gabbert is expected to miss multiple games with a serious hamstring injury.
NFL Network reported Monday that Gabbert heard his hamstring make an audible pop and could miss an "extended period" with his latest injury.
Chad Henne, who replaced Gabbert in Sunday's loss at St. Louis and started two games earlier this season with Gabbert recovering from a lacerated hand, would start Week 6 against the Denver Broncos.
Jacksonville opened as a record 28-point underdog.
Gabbert, a first-round draft pick in 2011, missed six games due to injury last season.