PHILADELPHIA -- Rookie left-hander Jeff Locke combined with three relievers on a four-hitter Tuesday night as the Pittsburgh Pirates blanked the Philadelphia Phillies 2-0.
The 25-year-old Locke (2-1) allowed two hits in six innings. He struck out six, walked two and also hit a batter.
Tony Watson worked a 1-2-3 seventh, striking out two. Mark Melancon followed with a scoreless eighth and Jason Grilli retired the Phils in order in the ninth for his eighth save.
Pittsburgh's Gaby Sanchez hit his second homer of the season, a solo blast off Cole Hamels (0-3) with one out in the eighth inning, as the Pirates won for the fifth time in seven games and the eighth time in 11.
Hamels pitched eight innings, allowing seven hits and two runs. He struck out six and walked one. It is the first time in his career he has started a season 0-3, and the first time the Phils have ever dropped five straight starts on his part.
Phillies third baseman Michael Young extended his hitting streak to 14 games with an eighth-inning single off Melancon.
Pittsburgh third baseman Brandon Inge, activated from the disabled list earlier in the day, laced a double to deep center in the fourth inning to score Neil Walker, who led off the inning with an infield hit.
The Phillies wasted a leadoff triple by John Mayberry Jr. in their half of the fourth. Ben Revere grounded into a fielder's choice, with Inge gunning down Mayberry at the plate, and Erik Kratz bounced into an inning-ending double play.
NOTES: LHP Jesse Biddle, considered the top prospect in the Phillies' organization, struck out 16 while allowing one hit over seven innings Monday as Double-A Reading beat Harrisburg 3-2. Biddle retired the first 19 hitters he faced, and his strikeout total was a career high and a modern-day Reading record. "Biddle's got a chance to be a special pitcher," Phillies manager Charlie Manuel said before Tuesday's game, adding that the 6-foot-5, 235-pound Biddle is a "bigger, stronger" version of Hamels. ... Inge, who had been out due to an injured right scapula, hit .150 during his 18-game rehab assignment. OF Alex Presley was optioned to Triple-A Indianapolis to make room on the Pirates' roster.