TORONTO -- Nick Markakis and J.J. Hardy each drove in three runs and right-hander Chris Tillman pitched five innings as the Baltimore Orioles defeated the Toronto Blue Jays 10-6 on Friday.
Left-hander Sean Nolin (0-1) who was making his major-league debut allowed seven hits and six runs in 1 1/3 innings after the Blue Jays (20-28) called him up from Double-A New Hampshire.
The Orioles (26-22) hit four homers. Nolin gave up . Hardy's three-run blast in the first. Ramon Ortiz allowed a solo shot by Chris Davis and a two-run drive by Danny Valencia in the third, and Brad Lincoln gave up a solo shot by Adam Jones in the sixth.
Tillman (4-2) allowed three runs and 10 hits including home runs by Melky Cabrera and Brett Lawrie before a crowd of 25,104 at Rogers Centre.
Adam Lind also homered for the Blue Jays who outhit the Orioles, 17-16. Markakis, Manny Machado and Davis each had three hits for the Orioles.
Jose Bautista and Lind each had three hits for the Blue Jays.
Left-hander Brian Matusz took over in the sixth and gave up a two-out walk to Emilio Bonifacio, an RBI double to Munenori Kawasaki and an RBI single to Cabrera as Toronto cut the lead to 10-5.
Lind led off the seventh with his fourth homer of the season against right-hander Tommy Hunter to reduce Baltimore's lead to four runs.
The teams have split the first two games of a four-game series.
Nolin was welcomed to the majors by three straight hits -- singles by Markakis and Machado and Hardy's ninth homer of the season.
The Blue Jays trimmed the lead to 3-1 in their half of the first when Cabrera hit his second homer of the season and the first of his career leading off a game.
Nolin did not survive the second as Markakis hit a three-run double to give the Orioles a 6-1 lead. Nolin was replaced by Ortiz, who turned 40 on Thursday.
The Blue Jays answered with two runs in their half of the second. Lawrie led off with his fifth homer of the season. Colby Rasmus doubled and scored on a single by Emilio Bonifacio.
Davis led off the third with his American League-leading 16th homer of the season. And after Matt Wieters walked, Valencia hit his first homer of the season and the Orioles led 9-3.
Lawrie and manager John Gibbons were ejected at the end of the third. Lawrie threw his helmet to the ground and tossed a batting glove after a called third strike. Gibbons argued with plate umpire Dan Bellino and received his third ejection of the season. Mark DeRosa took over at third.
NOTES: The Blue Jays put LHP Darren Oliver (left shoulder strain) on the 15-day disabled list, retroactive to May 19, which opened a spot on the 25-man roster for Nolin. ... LHP J.A. Happ (skull fracture, sprained right knee) was moved to the 60-day DL to open a spot on the 40-man roster for Nolin. ... Jones (groin), who was used as a DH for three games, was back in the field for the Orioles. Since the start of the 2012 season, Jones had hit six homers at Rogers Centre before Friday's game, the most of any visiting player in that span. ... Blue Jays RHP R.A. Dickey (4-5, 4.50 ERA) starts against Orioles RHP Freddy Garcia (0-2, 4.84 ERA) on Saturday.