University of Maryland regents unanimously approved the school's move to the Big Ten on Monday, the Chicago Tribune reported.
Once the school is formally invited, the move is expected to take effect in the 2014-15 season.
Also, Big East Conference sources told ESPN that Rutgers will be announced as the 14th member of the Big Ten on Tuesday.
Moving out of the ACC would reportedly cost Maryland a $50 million exit fee.
School president Wallace Loh, who was heading Maryland's communications with Big Ten officials, formerly was a provost at the University of Iowa, a Big Ten member.
Gaining the state universities of Maryland and New Jersey would be a coup for the Big Ten in terms of television interest.
The conference grew to 12 schools when Penn State (1990) and Nebraska (2010) joined.