A day after his late heroics turned what seemed like a certain loss into a victory, Ozuna looks to extend his 14-game hitting streak in Wednesday's series finale when the visiting Marlins go for their fourth win in five games.
Arizona starters, 14th in the NL with a 4.62 ERA, have allowed two runs over 19 2-3 innings in the last three games. Vidal Nuno, acquired from the New York Yankees on Sunday, gave up three hits over seven innings in his debut Tuesday.
The Diamondbacks (38-54) were on the verge of their first three-game run since a road sweep in Colorado from June 3-5 before Ozuna delivered a two-strike, two-out, two-run home run off closer Addison Reed for a 2-1 victory.
''He got a good pitch to hit and didn't miss it,'' Miami manager Mike Redmond said. ''In this ballpark you can do some damage on one swing.''
Ozuna, 4 for 8 in this series, also had a fourth-inning double to extend his hitting streak to 14 games - the longest active in the majors. He's batting .370 with three homers in that span.
The outfielder will try to stay hot as the Marlins (44-46) seek their third straight series victory, but he's fanned twice in his two career at-bats against Arizona's Josh Collmenter (7-5, 3.98 ERA).
Collmenter had posted a 1.59 ERA while earning wins in three consecutive appearances - one in relief - before allowing five runs and a season-high 11 hits over six-plus innings in Friday's 5-2 loss at Atlanta.
The right-hander, though, has pitched well at Chase Field, going 4-1 with a 3.05 ERA in his last seven starts. In contrast, he's 2-3 with a 5.18 mark in his past seven on the road.
Collmenter has allowed one hit over seven scoreless innings in two relief appearances against the Marlins.
Garrett Jones has a home run in three career at-bats versus Collmenter dating to his time with Pittsburgh. Jones is 3 for 5 with two doubles in this series after flying out as a pinch hitter Tuesday.
All-Star Giancarlo Stanton went 0 for 3, leaving him 4 for 28 with one RBI in his last seven contests. Casey McGehee also went hitless, ending his career-best 14-game hitting streak and major league-best 21-game streak on the road.
Miami's Nathan Eovaldi (5-4, 3.75) hopes to turn things around after struggling with a 5.70 ERA in his last five starts. He had posted a 1.93 mark over his previous four.
Eovaldi, who has a 2.05 ERA in his last four road outings, is 2-0 with a 2.65 ERA in three career starts against the Diamondbacks.
The right-hander will likely have to deal with All-Star Paul Goldschmidt, who hit his major league-leading 34th double Tuesday to extend his hitting streak to eight games. He's 14 for 29 with six doubles over that stretch.
The Diamondbacks were 1 for 12 with runners in scoring position Tuesday after going 5 for 10 in a series-opening 9-1 win.
''We score one run in one inning,'' manager Kirk Gibson said, ''so that makes everything else look magnified.''